Oxidative stress in granulosa-lutein cells from in vitro fertilization patients

J Ávila, R González-Fernández, D Rotoli… - Reproductive …, 2016 - journals.sagepub.com
Ovarian aging is associated with gradual follicular loss by atresia/apoptosis. Increased
production of toxic metabolites such as reactive oxygen species (ROS) and reactive nitrogen …

Protective effect of resveratrol against oxidative damage to ovarian reserve in female Sprague–Dawley rats

P Özcan, C Fıçıcıoğlu, ÖK Yıldırım, F Özkan… - Reproductive …, 2015 - Elsevier
An increased accumulation of intracellular levels of reactive oxygen species with time may
play an important role in the process of ageing. The antioxidant properties of resveratrol are …

Oocyte aging underlies female reproductive aging: biological mechanisms and therapeutic strategies

H Igarashi, T Takahashi, S Nagase - Reproductive medicine and biology, 2015 - Springer
In recent years, postponement of marriage and childbearing in women of reproductive age
has led to an increase in the incidence of age-related infertility. The reproductive aging …

Oxidative damage increases and antioxidant gene expression decreases with aging in the mouse ovary

J Lim, U Luderer - Biology of reproduction, 2011 - academic.oup.com
Oxidative stress has been implicated in various aspects of aging, but the role of oxidative
stress in ovarian aging remains unclear. Our previous studies have shown that the initiation …

[HTML][HTML] Can ovarian aging be delayed by pharmacological strategies?

J Zhang, Q Chen, D Du, T Wu, J Wen, M Wu… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Aging has been regarded as a treatable condition, and delaying aging could prevent some
diseases. Ovarian aging, a special type of organ senescence, is the earliest-aging organ, as …

Oxidative stress and ageing of the post-ovulatory oocyte

T Lord, RJ Aitken - Reproduction, 2013 - rep.bioscientifica.com
With extended periods of time following ovulation, the metaphase II stage oocyte
experiences deterioration in quality referred to as post-ovulatory oocyte ageing. Post …

The antioxidant curcumin postpones ovarian aging in young and middle-aged mice

SH Azami, H Nazarian, MA Abdollahifar… - Reproduction …, 2020 - CSIRO Publishing
Reproductive senescence is accompanied by a reduced number and quality of ovarian
follicles in response to the accumulation of free radicals and the process of apoptosis …

[HTML][HTML] Resveratrol increases resistance of mouse oocytes to postovulatory aging in vivo

QX Liang, YH Lin, CH Zhang, HM Sun, L Zhou… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
After ovulation, metaphase II oocytes undergo a time-dependent deterioration in vivo or in
vitro, which is referred to as postovulatory oocyte aging, a process during which a series of …

Impact of stress on oocyte quality and reproductive outcome

S Prasad, M Tiwari, AN Pandey, TG Shrivastav… - Journal of biomedical …, 2016 - Springer
Stress is an important factor that affects physical and mental status of a healthy person
disturbing homeostasis of the body. Changes in the lifestyle are one of the major causes that …

[HTML][HTML] Excessive oxidative stress in cumulus granulosa cells induced cell senescence contributes to endometriosis-associated infertility

X Lin, Y Dai, X Tong, W Xu, Q Huang, X Jin, C Li… - Redox biology, 2020 - Elsevier
Endometriosis an important cause of female infertility and seriously impact physical and
psychological health of patients. Endometriosis is now considered to be a public health …