Characterization of Toll-like receptors in primary lung epithelial cells: strong impact of the TLR3 ligand poly (I: C) on the regulation of Toll-like receptors, adaptor …
M Ritter, D Mennerich, A Weith, P Seither - Journal of inflammation, 2005 - Springer
Background Bacterial and viral exacerbations play a crucial role in a variety of lung diseases
including COPD or asthma. Since the lung epithelium is a major source of various …
including COPD or asthma. Since the lung epithelium is a major source of various …
Distinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells
J Bérubé, C Bourdon, Y Yao, S Rousseau - Cellular signalling, 2009 - Elsevier
Inflammation is a central feature of many respiratory diseases. Airway epithelial cells are
exposed to many agents present in the air that can alter their function and have important …
exposed to many agents present in the air that can alter their function and have important …
Long-term activation of TLR3 by poly (I: C) induces inflammation and impairs lung function in mice
NC Stowell, J Seideman, HA Raymond, KA Smalley… - Respiratory …, 2009 - Springer
Background The immune mechanisms associated with infection-induced disease
exacerbations in asthma and COPD are not fully understood. Toll-like receptor (TLR) 3 has …
exacerbations in asthma and COPD are not fully understood. Toll-like receptor (TLR) 3 has …
[HTML][HTML] The role of toll-like receptors in the production of cytokines by human lung macrophages
S Grassin-Delyle, C Abrial, H Salvator… - Journal of innate …, 2020 - karger.com
Background: The Toll-like receptor (TLR) family is involved in the recognition of and
response to microbial infections. These receptors are expressed in leukocytes. TLR …
response to microbial infections. These receptors are expressed in leukocytes. TLR …
Activation of airway epithelial cells by toll-like receptor agonists
Q Sha, AQ Truong-Tran, JR Plitt, LA Beck… - American journal of …, 2004 - atsjournals.org
Toll-like receptors (TLR) play an important role in pathogen recognition and innate immunity.
We investigated the presence and function of TLRs in the BEAS-2B airway epithelial cell line …
We investigated the presence and function of TLRs in the BEAS-2B airway epithelial cell line …
Differential expression of Toll-like receptors on human alveolar macrophages and autologous peripheral monocytes
Abstract Background Toll-like receptors (TLRs) are critical components in the regulation of
pulmonary immune responses and the recognition of respiratory pathogens such as …
pulmonary immune responses and the recognition of respiratory pathogens such as …
Gene expression of Toll-like receptors and associated molecules induced by inflammatory stimuli in the primary alveolar macrophage
K Oshikawa, Y Sugiyama - Biochemical and biophysical research …, 2003 - Elsevier
We investigated the expression of Toll-like receptors (TLRs) and associated signaling
molecules in inflammatory stimuli-activated murine primary alveolar macrophage (AM) in …
molecules in inflammatory stimuli-activated murine primary alveolar macrophage (AM) in …
Pseudomonas aeruginosa LPS or Flagellin Are Sufficient to Activate TLR-Dependent Signaling in Murine Alveolar Macrophages and Airway Epithelial Cells
E Raoust, V Balloy, I Garcia-Verdugo, L Touqui… - PloS one, 2009 - journals.plos.org
Background The human lung is exposed to a large number of airborne pathogens as a
result of the daily inhalation of 10,000 liters of air. Innate immunity is thus essential to defend …
result of the daily inhalation of 10,000 liters of air. Innate immunity is thus essential to defend …
Expression of functional toll-like receptor-2 and-4 on alveolar epithelial cells
L Armstrong, ARL Medford, KM Uppington… - American journal of …, 2004 - atsjournals.org
The recognition of potentially harmful microorganisms involves the specific recognition of
pathogen-associated molecular patterns (PAMPs) and the family of Toll-like receptors …
pathogen-associated molecular patterns (PAMPs) and the family of Toll-like receptors …
TLR3 activation stimulates cytokine secretion without altering agonist-induced human small airway contraction or relaxation
Respiratory infections exacerbate chronic lung diseases promoting airway inflammation and
hyperreactivity. Toll-like receptor 3 (TLR3) recognizes viral double-stranded (ds) RNA such …
hyperreactivity. Toll-like receptor 3 (TLR3) recognizes viral double-stranded (ds) RNA such …