Human immunodeficiency virus type 1 (HIV-1) establishes a persistent, nonproductive state
within a small population of memory CD4+ cells. The transcription factor LSF binds to …

Human immunodeficiency virus type 1 (HIV-1) establishes a persistent, nonproductive state
within a small population of memory CD4+ cells. The transcription factor LSF binds to …

Enigmatic mechanisms restore the resting state in activated lymphocytes following human
immunodeficiency virus type 1 (HIV-1) infection, rarely allowing persistent nonproductive …

The host factor LSF represses the human immunodeficiency virus type 1 long terminal
repeat (LTR) by mediating recruitment of histone deacetylase. We show that pyrrole …

LSF (late SV40 factor) is a mammalian transcription factor that regulates expression of both
viral genomes and cellular genes, including that encoding thymidylate synthase, a critical …

Cells latently infected with HIV represent a currently insurmountable barrier to viral
eradication in infected patients. Using the J‐Lat human T‐cell model of HIV latency, we have …

Background The generation of over 69 spliced HIV-1 mRNAs from one primary transcript by
alternative RNA splicing emphasizes the central role that RNA processing plays in HIV-1 …

During HIV-1 infection a population of latently infected cells is established. This population is
the major obstacle preventing total eradication of the virus from AIDS patients. HIV-1 latency …

Latently infected cells rapidly initiate HIV transcription after exposure to signals that induce
NF‐κB. To investigate the role of TFIIH during HIV reactivation in vivo, we developed a …

Human immunodeficiency virus type-1 (HIV-1) can either undergo a lytic pathway to cause
productive systemic infections or enter a latent state in which the integrated provirus remains …