[HTML][HTML] Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation

R Divella, R De Luca, I Abbate, E Naglieri… - Journal of …, 2016 - ncbi.nlm.nih.gov
Adipose tissue in addition to its ability to keep lipids is now recognized as a real organ with
both metabolic and endocrine functions. Recent studies demonstrated that in obese animals …

Obesity as a major risk factor for cancer

G De Pergola, F Silvestris - Journal of obesity, 2013 - Wiley Online Library
The number of cancer cases caused by being obese is estimated to be 20% with the
increased risk of malignancies being influenced by diet, weight change, and body fat …

Obesity and cancer mechanisms: tumor microenvironment and inflammation

NM Iyengar, A Gucalp, AJ Dannenberg… - Journal of clinical …, 2016 - ascopubs.org
Purpose There is growing evidence that inflammation is a central and reversible mechanism
through which obesity promotes cancer risk and progression. Methods We review recent …

Mechanisms linking excess adiposity and carcinogenesis promotion

AI Pérez-Hernández, V Catalán… - Frontiers in …, 2014 - frontiersin.org
Obesity constitutes one of the most important metabolic diseases being associated to insulin
resistance development and increased cardiovascular risk. Association between obesity …

Obesity and cancer: the role of dysfunctional adipose tissue

RCM Van Kruijsdijk, E Van Der Wall… - … , biomarkers & prevention, 2009 - AACR
Overweight and obesity are health problems of epidemic proportions, increasing the risk not
only of cardiovascular disease and type 2 diabetes mellitus but also of various types of …

Obesity, inflammation, and cancer

T Deng, CJ Lyon, S Bergin, MA Caligiuri… - Annual Review of …, 2016 - annualreviews.org
Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including cancer, and is increasingly recognized as a growing cause of preventable cancer …

Signals from the adipose microenvironment and the obesity–cancer link—a systematic review

C Himbert, M Delphan, D Scherer, LW Bowers… - Cancer prevention …, 2017 - AACR
Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

From obesity to cancer: a review on proposed mechanisms

Z Tahergorabi, M Khazaei, M Moodi… - Cell biochemistry and …, 2016 - Wiley Online Library
Nowadays, obesity is considered as a serious and growing global health problem. It is
documented that the overweight and obesity are major risk factors for a series of …

Adipocytes: impact on tumor growth and potential sites for therapeutic intervention

S Hefetz-Sela, PE Scherer - Pharmacology & therapeutics, 2013 - Elsevier
The prevalence of obesity has increased dramatically in recent decades, reaching epidemic
proportions. It is becoming clear that obesity is associated not only with type 2 diabetes …

Cytokines, obesity, and cancer: new insights on mechanisms linking obesity to cancer risk and progression

CA Gilbert, JM Slingerland - Annual review of medicine, 2013 - annualreviews.org
Obesity is a problem of epidemic proportions in many developed nations. Increased body
mass index and obesity are associated with a significantly worse outcome for many cancers …