OBJECTIVE: To evaluate the relationship between mitochondrial gene expression of
oocytes/embryos and their fertilizability in unfertilized oocytes, arrested embryos, and …

Mitochondrial DNA content varies considerably in oocytes, even when collected from the
same patient. In the present study, real-time quantitative polymerase chain reaction analysis …

It is likely that there is an association between the fitness of mitochondria and their ability to
support normal cellular function. Oocytes are greatly enriched in the number of mitochondria …

Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …

Background: The aim of the current study was to assess the mRNA levels of two
mitochondria-related genes, including nuclear-encoded NRF1 (nuclear respiratory factor 1) …

Mitochondria are well known as 'the powerhouses of the cell'. Indeed, their major role is
cellular energy production driven by both mitochondrial and nuclear DNA. Such a feature …

The present study was designed to determine whether controlled ovarian hyperstimulation
(COH) and in vitro maturation (IVM), two common clinical procedures in human IVF …

Mitochondrial DNA (mtDNA) point mutations are known to accumulate in an age-dependent
fashion in somatic tissues. This study investigated whether a point mutation (T414G) in the …

Oocyte quality has long been considered as a main limiting factor for in vitro fertilization
(IVF). In the past decade, extensive observations demonstrated that the mitochondrion plays …

The mitochondrion undergoes significant functional and structural changes, as well as an
increase in number, during preimplantation embryonic development. The mitochondrion …