[HTML][HTML] Genetics of oocyte maturation defects and early embryo development arrest
OA Solovova, VB Chernykh - Genes, 2022 - mdpi.com
Various pathogenic factors can lead to oogenesis failure and seriously affect both female
reproductive health and fertility. Genetic factors play an important role in folliculogenesis and …
reproductive health and fertility. Genetic factors play an important role in folliculogenesis and …
[HTML][HTML] Vitrification of mouse MII oocyte decreases the mitochondrial DNA copy number, TFAM gene expression and mitochondrial enzyme activity
M Amoushahi, M Salehnia, SJ Mowla - Journal of Reproduction & …, 2017 - ncbi.nlm.nih.gov
Background: The objective of this study was determination of the changes in the reactive
oxygen species (ROS) level, mitochondrial DNA (mtDNA) copy number and enzyme activity …
oxygen species (ROS) level, mitochondrial DNA (mtDNA) copy number and enzyme activity …
The importance of mitochondrial metabolic activity and mitochondrial DNA replication during oocyte maturation in vitro on oocyte quality and subsequent embryo …
H Ge, TL Tollner, Z Hu, M Dai, X Li… - Molecular …, 2012 - Wiley Online Library
Mitochondrial metabolic capacity and DNA replication have both been shown to affect
oocyte quality, but it is unclear which one is more critical. In this study, immature oocytes …
oocyte quality, but it is unclear which one is more critical. In this study, immature oocytes …
[HTML][HTML] Mitochondria as a biomarker for IVF outcome
J Kim, E Seli - Reproduction, 2019 - rep.bioscientifica.com
Mitochondria play an essential role in generating energy for embryo development and
maintaining embryo metabolism through key cellular functions including ion homeostasis …
maintaining embryo metabolism through key cellular functions including ion homeostasis …
Mitochondria: potential roles in embryogenesis and nucleocytoplasmic transfer.
JM Cummins - Human reproduction update, 2001 - europepmc.org
This review examines current understanding of mammalian mitochondria and mitochondrial
DNA in the light of new reproductive technologies. Mitochondria are central to ageing …
DNA in the light of new reproductive technologies. Mitochondria are central to ageing …
Mitochondrial aggregation patterns and activity in human oocytes and preimplantation embryos
M Wilding, B Dale, M Marino, L di Matteo… - Human …, 2001 - academic.oup.com
Mitochondria play a vital role in the metabolism of energy-containing compounds in the
oocyte cytoplasm to provide adenosine trisphosphate for fertilization and preimplantation …
oocyte cytoplasm to provide adenosine trisphosphate for fertilization and preimplantation …
Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in vitro
Oocyte mitochondrial dysfunction has been proposed as a cause of high levels of
developmental retardation and arrest that occur in human preimplantation embryos …
developmental retardation and arrest that occur in human preimplantation embryos …
[HTML][HTML] Mitochondrial DNA copy number in cleavage stage human embryos—impact on infertility outcome
A retrospective case control study was undertaken at the molecular biology department of a
private center for reproductive medicine in order to determine whether any correlation exists …
private center for reproductive medicine in order to determine whether any correlation exists …
Mitochondrial function in the human oocyte and embryo and their role in developmental competence
J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …
and early embryogenesis is emerging from basic research in model species and from …
Mitochondrial function of human embryo: Decline in their quality with maternal aging
S Hashimoto, Y Morimoto - Reproductive Medicine and Biology, 2022 - Wiley Online Library
Background Female fertility declines with age, due to increased chromosomal aneuploidy
and possible reduced mitochondrial function in the embryo. Methods This review outlines …
and possible reduced mitochondrial function in the embryo. Methods This review outlines …