Polycystic ovary syndrome (PCOS) is a complex, but relatively common endocrine disorder
associated with chronic anovulation, hyperandrogenism, and micro-polycystic ovaries. In …

Objective To reveal the relationship between mitochondrial function in cumulus cells (CCs)
and the aging-related decline in ovarian function and reproductive capacity. Design …

Background Recent work has shown that mitochondrial biogenesis and mitochondrial
functions are critical determinants of embryonic development. However, the expression of …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte
quality which is important for fertilization and development into viable offspring. Quality …

Mitochondrial dysfunction may be acquired or inherited by oocytes without detectable
morphological abnormalities. This pathology may account for some examples of …

Many infertility specialists support the existence of a relationship between the levels of
mitochondrial DNA and the quality of the blastocysts. Despite the extensive use of pre …

In vitro culture (IVC), used in assisted reproductive technologies, is a major environmental
stress on the embryo. To evaluate the effect of IVC on mitochondrial transcription and the …

OBJECTIVE: To determine the relationship between the intrinsic mitochondrial ΔΨ of human
embryos and the embryo karyotype. DESIGN: Analysis of mitochondrial ΔΨ of living …

Mitochondria affect numerous aspects of mammalian reproduction. We investigated whether
the decrease in oocyte quality associated with aging is related to altered mitochondria …