Antiviral activities of individual murine IFN-α subtypes in vivo: intramuscular injection of IFN expression constructs reduces cytomegalovirus replication
WS Yeow, CM Lawson, MW Beilharz - The Journal of Immunology, 1998 - journals.aai.org
The IFN-α cytokines belong to a multigene family. However, the in vivo biological functions
of each of the IFN-α subtypes is unknown. Recently, we developed an experimental model …
of each of the IFN-α subtypes is unknown. Recently, we developed an experimental model …
Potential roles played by IL-6 in hepatitis B infection
M Ebrahim, V Bagheri, MK Arababadi - Future Virology, 2014 - Taylor & Francis
Hepatitis B is a main disorder of the liver, which is induced by HBV. Hepatitis B can induce
liver diseases, such as inflammation, cirrhosis and hepatocellular carcinoma (HCC). Recent …
liver diseases, such as inflammation, cirrhosis and hepatocellular carcinoma (HCC). Recent …
Regulation of innate immunity against hepatitis C virus infection
Chronic hepatitis C virus (HCV) infection is a global public health problem. HCV infection is
treated with type I interferon (IFN), a natural product that is produced by cells during virus …
treated with type I interferon (IFN), a natural product that is produced by cells during virus …
[HTML][HTML] Interferon-stimulated genes as enhancers of antiviral innate immune signaling
The ability of a host to curb a viral infection is heavily reliant on the effectiveness of an initial
antiviral innate immune response, resulting in the upregulation of interferon (IFN) and …
antiviral innate immune response, resulting in the upregulation of interferon (IFN) and …
IL-1β attenuates IFN-αβ-induced antiviral activity and STAT1 activation in the liver: involvement of proteasome-dependent pathway
Z Tian, X Shen, H Feng, B Gao - The Journal of Immunology, 2000 - journals.aai.org
IFN-αβ is the only established treatment for viral hepatitis; however, more than 60% of
patients are poorly responsive. Because viral hepatitis is associated with inflammation, we …
patients are poorly responsive. Because viral hepatitis is associated with inflammation, we …
Simultaneous or prior activation of intrahepatic type I interferon signaling leads to hepatitis b virus persistence in a mouse model
S Zou, Y Du, S Huang, M Chen, X Yang, S Li… - Journal of …, 2021 - Am Soc Microbiol
It remains controversial how interferon (IFN) response contributes to hepatitis B virus (HBV)
control and pathogenesis. A previous study identified that hydrodynamic injection (HI) of …
control and pathogenesis. A previous study identified that hydrodynamic injection (HI) of …
To interfere and to anti-interfere: the interplay between hepatitis C virus and interferon
Y He, MG Katze - Viral immunology, 2002 - liebertpub.com
As popular strategies used by numerous viruses, interception of interferon (IFN) signaling
and inhibition of IFN-induced antiviral functions allow viruses to evade the host immune …
and inhibition of IFN-induced antiviral functions allow viruses to evade the host immune …
[HTML][HTML] Inhibition of IFN-γ signaling by an Epstein-Barr virus immediate-early protein
TE Morrison, A Mauser, A Wong, JPY Ting, SC Kenney - Immunity, 2001 - cell.com
Viruses have evolved elaborate mechanisms to target many aspects of the host's immune
response. The cytokine IFN-γ plays a central role in resistance of the host to infection via …
response. The cytokine IFN-γ plays a central role in resistance of the host to infection via …