Introduction: Male infertility affects about 7% of the general male population, and it is a
multifactorial, polygenic pathological condition. Known genetic factors, accounting for about …

Objective: The main purpose of this study is to detect the frequency and type of both
chromosomal abnormalities and Y chromosome microdeletions in patients with severe male …

Infertility is one of the most serious social problems facing advanced nations. In general,
approximate half of all cases of infertility are caused by factors related to the male partner …

Studies into the mechanisms underlying spermatogenesis, the process by which
spermatogonia undergo meiosis to become spermatozoa, have identified a number of …

Male infertility represents one of the clearest examples of a complex disease with a
substantial genetic basis. Numerous male mouse models, mutation screening and …

Background At present, one out of six couples is infertile, and in 50% of cases, infertility is
attributed to male infertility factors. Genetic abnormalities are found in 10%‐20% of patients …

BACKGROUND Infertility is a major issue in human reproductive health, affecting an
estimated 15% of couples worldwide. Infertility can result from disorders of sex development …

As with many other diseases, genetic testing in human azoospermia was initially restricted to
karyotype analyses (leading to diagnostic chromosome rearrangement tests for Klinefelter …

A major chromosomal abnormality was observed in 10.3% of subfertile men in this study.
This result is similar to a previous survey using the same criteria for selection of probands …

Infertility affects about 7% of all men. The etiology of impaired sperm production and function
can be related to factors acting at pre-testicular, post-testicular or directly at the testicular …