Novel Pyridyl–Oxazole Carboxamides: Toxicity Assay Determination in Fungi and Zebrafish Embryos

S Chen, DL Zhang, CL Ren, WQ Zou, XY Tian, XH Du… - Molecules, 2021 - mdpi.com
Eight novel pyridyl–oxazole carboxamides were evaluated against fungi and displayed
good fungicidal activities against Botrytis cinereal and Rhizoctonia solani. Preliminary …

Benzamides substituted with quinoline-linked 1, 2, 4-oxadiazole: Synthesis, biological activity and toxicity to zebrafish embryo

BL Sun, YY Wang, S Yang, MT Tu, YY Shao, Y Hua… - Molecules, 2022 - mdpi.com
To develop new compounds with high activity, broad spectrum and low-toxicity, 17
benzamides substituted with quinoline-linked 1, 2, 4-oxadiazole were designed using the …

1, 2, 4-Oxadiazole-based bio-isosteres of benzamides: Synthesis, biological activity and toxicity to zebrafish embryo

S Yang, CL Ren, TY Ma, WQ Zou, L Dai… - International Journal of …, 2021 - mdpi.com
To discover new compounds with broad spectrum and high activity, we designed a series of
novel benzamides containing 1, 2, 4-oxadiazole moiety by bioisosterism, and 28 …

Synthesis, Biological Activity, and Toxicity to Zebrafish Embryo of Benzamides Substituted with 1, 2, 4-Oxadiazole-Linked Pyrazole

Y Wang, C Wu, Z Li, J Wu, Y Chen, M Li… - … Agricultural Science & …, 2023 - ACS Publications
To explore novel pesticidal lead compounds with potential activity, a series of new
benzamide compounds substituted with 1, 2, 4-oxadiazole-linked pyrazole were designed …

Synthesis, biological activity and toxicity to zebrafish of benzamides substituted with pyrazole-linked 1, 2, 4-oxadiazole

Y Shao, M Tu, S Yang, Y Wang, B Sun, J Shi, C Tan… - RSC …, 2022 - pubs.rsc.org
To find pesticidal lead compounds with high activity, a series of novel benzamides
substituted with pyrazole-linked 1, 2, 4-oxadiazole was designed and synthesized by using …

Design, synthesis and bioactivity evaluation of novel β-carboline 1, 3, 4-oxadiazole derivatives

ZJ Zhang, JJ Zhang, ZY Jiang, GH Zhong - Molecules, 2017 - mdpi.com
A series of novel β-carboline 1, 3, 4-oxadiazole derivatives were designed and synthesized,
and the in vitro cytotoxic activity against Sf9 cells and growth inhibitory activity against …

Design, synthesis and fungicidal activity of pyrazole–thiazole carboxamide derivatives

Z Hao, B Yu, W Gao, H Chen, D Yang, Y Lv, Y Zhang… - Molecular Diversity, 2022 - Springer
Twenty-one novel pyrazole–thiazole carboxamide derivatives were rationally designed and
synthesized. Bioassay results indicated that 6d (EC 50= 5.11 μg/mL) and 6j (EC 50= 8.14 …

Investigation of novel pyrazole carboxamides as new apoptosis inducers on neuronal cells in Helicoverpa zea

Y Ren, N Yang, Y Yue, H Jin, K Tao, T Hou - Bioorganic & Medicinal …, 2018 - Elsevier
Novel pyrazole carboxamides with a diarylamine-modified scaffold were modified based on
the bixafen (Bayer) fungicide, which has excellent activity against Rhizoctonia solani …

Synthesis and biological activities of novel pyrazole carboxamides containing an aryloxypyridyl ethylamine module

Y Liu, S Du, X Xu, L Qiu, S Hong, B Fu… - Journal of Agricultural …, 2024 - ACS Publications
Pyrazole carboxamide is widely utilized in agricultural crop protection. In this research, we
synthesized two classes of compounds, namely, pyrazole-5-carboxamide (4a) and pyrazole …

Design, synthesis and biological evaluation of 1H-pyrazole-5-carboxamide derivatives as potential fungicidal and insecticidal agents

D Huang, M Huang, W Liu, A Liu, X Liu, X Chen, H Pei… - Chemical Papers, 2017 - Springer
A series of novel 1H-pyrazole-5-carboxamide compounds containing the phenyl thiazole
moiety were designed and synthesized by a facile method, and their structures were …