Objectives We aimed to assess the relationships between early-life tobacco smoke
exposures and the incident risk of type 2 diabetes (T2D) in later life as well as the joint …

Many biomarkers are associated with type 2 diabetes (T2D) risk in epidemiological
observations. The aim of this study was to identify and summarize current evidence for …

Observational studies have suggested that smoking is associated with coronary artery
disease (CAD). 1, 2 Compared with non-smokers, there is a 29% to 80% increased risk of …

Cigarette smoking has been shown to be a health hazard. In addition to being considered a
negative lifestyle behavior, studies have shown that cigarette smoking has been linked to …

Background Susceptibility to type 2 diabetes may be conferred by genetic variants having
modest effects on risk. Genome-wide fixed marker arrays offer a novel approach to detect …

Background and aims Cardiometabolic disorders (CMD) arise from a constellation of
features such as increased adiposity, hyperlipidemia, hypertension and compromised …

Background Although smoking behavior is known to affect body mass index (BMI), the
potential for smoking to influence genetic associations with BMI is largely unexplored …

Abstract Objective Type 2 diabetes (T2D) is caused by both genetic and cardiometabolic risk
factors. However, the magnitude of the genetic predisposition of T2D in the Chinese …

Genome-wide association studies (GWAs) for type 2 diabetes (T2D) have been successful in
identifying many loci with robust association signals. Nevertheless, there is a clear need for …

Background Common metabolic diseases, including type 2 diabetes, coronary artery
disease, and hypertension, arise from disruptions of the body's metabolic homeostasis, with …