Manipulation of in Vitro Angiogenesis Using Peptide-Coated Gold Nanoparticles

D Bartczak, OL Muskens, T Sanchez-Elsner… - ACS …, 2013 - ACS Publications
We demonstrate the deliberate activation or inhibition of in vitro angiogenesis using
functional peptide coated gold nanoparticles. The peptides, anchored to oligo-ethylene …

Peptide-coated gold nanoparticles for modulation of angiogenesis in vivo

C Roma-Rodrigues, A Heuer-Jungemann… - International journal …, 2016 - Taylor & Francis
In this work, peptides designed to selectively interact with cellular receptors involved in the
regulation of angiogenesis were anchored to oligo-ethylene glycol-capped gold …

Receptor‐mediated interactions between colloidal gold nanoparticles and human umbilical vein endothelial cells

D Bartczak, T Sanchez‐Elsner, F Louafi, TM Millar… - Small, 2011 - Wiley Online Library
A new strategy to manipulate cell operations is demonstrated, based on membrane‐receptor‐
specific interactions between colloidal peptide‐capped gold nanoparticles and human …

Bioconjugated gold nanoparticles accelerate the growth of new blood vessels through redox signaling

SK Nethi, S Mukherjee, V Veeriah, AK Barui… - Chemical …, 2014 - pubs.rsc.org
We have designed and developed novel pro-angiogenic bio-synthesized gold
nanoconjugates (b-Au-HP) that make new blood vessels, as observed by several in vitro …

Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles

P Pedrosa, A Heuer-Jungemann, AG Kanaras… - Journal of …, 2017 - Springer
Background Anti-angiogenic therapy has great potential for cancer therapy with several FDA
approved formulations but there are considerable side effects upon the normal blood …

Gold nanoparticles and angiogenesis: molecular mechanisms and biomedical applications

RS Darweesh, NM Ayoub, S Nazzal - International journal of …, 2019 - Taylor & Francis
Angiogenesis is the formation of new blood vessels from pre-existing vessels. It is a highly
regulated process as determined by the interplay between pro-angiogenic and anti …

Gold and silver nanoparticles conjugated with heparin derivative possess anti-angiogenesis properties

MM Kemp, A Kumar, S Mousa, E Dyskin… - …, 2009 - iopscience.iop.org
Silver and gold nanoparticles display unique physical and biological properties that have
been extensively studied for biological and medical applications. Typically, gold and silver …

A reexamination of active and passive tumor targeting by using rod-shaped gold nanocrystals and covalently conjugated peptide ligands

X Huang, X Peng, Y Wang, Y Wang, DM Shin… - ACS …, 2010 - ACS Publications
The targeted delivery of nanoparticles to solid tumors is one of the most important and
challenging problems in cancer nanomedicine, but the detailed delivery mechanisms and …

Biologically inspired stealth peptide-capped gold nanoparticles

AK Nowinski, AD White, AJ Keefe, S Jiang - Langmuir, 2014 - ACS Publications
Introduction into the human body makes most nanoparticle systems susceptible to
aggregation via nonspecific protein binding. Here, we developed a peptide-capped gold …

Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size

E Oh, JB Delehanty, KE Sapsford, K Susumu… - ACS …, 2011 - ACS Publications
Numerous studies have examined how the cellular delivery of gold nanoparticles (AuNPs) is
influenced by different physical and chemical characteristics; however, the complex …