Oocyte mitochondria are increased in number, smaller, and rounder in appearance than
mitochondria in somatic cells. Moreover, mitochondrial numbers and activity are narrowly …

The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

There is a worldwide trend for women to have their first pregnancy later in life. However, as
oocyte quality declines with maternal aging, this trend leads to an increase in subfertility …

Our research has focused on promoting the development of compromised embryos by
transferring presumably normal ooplasm, including mitochondria, to oocytes during …

It is likely that there is an association between the fitness of mitochondria and their ability to
support normal cellular function. Oocytes are greatly enriched in the number of mitochondria …

As the vital organelles for cell energy metabolism, mitochondria are essential for oocyte
maturation, fertilization, and embryo development. Abnormalities in quantity, quality, and …

STUDY QUESTION What are the molecular differences between mitochondrial DNA
(mtDNA)-deficient and mtDNA-normal oocytes and how does mitochondrial …

The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …

In mammals, mitochondria and mitochondrial DNA (mtDNA) are transmitted through the
female germ line. Mature oocytes contain at least 100,000 copies of mtDNA, organized at 1 …

Oocyte quality is one of the most important factors involving in female reproduction. The
number of compromised oocytes will increase with maternal age, while mitochondrial …