Polyvinylpyrrolidone (PVP) and poly (ethylene glycol)(PEG) solid dispersions with
Felodipine or Hesperetin having up to 20wt% drug were prepared using solvent evaporation …

The present study describes the application of differential scanning calorimetry (DSC) to
ascertain the crystalline state of a drug with a melting point of~ 53° C after dispersion on …

Solid dispersions were prepared by a melting method from the water-insoluble model drugs
carbamazepine and nifedipine and polyethylene glycol 1500 (PEG 1500) or 1: 1 mixtures of …

Newly developed active pharmaceutical ingredients (APIs) are often poorly soluble in water.
As a result the bioavailability of the API in the human body is reduced. One approach to …

The present study explores the hypothesis that a polymer can affect the thermal stability of a
drug in solid polymer-drug dispersions. The hypothesis is tested in a systematic fashion by …

Solid dispersion literature, describing the mechanism of dissolution of drug–polyethylene
glycol dispersions, still shows some gaps;(A) only few studies include experiments …

The physical stability of amorphous molecular level solid dispersions will be influenced by
the miscibility of the components. The goal of this work was to understand the effects of …

The aim of this work was to develop a method which uses experimentally obtainable data to
predict the complete phase diagram of drug–polymer solid dispersion systems, for the first …

The objective of this study was to investigate the phase behavior of amorphous solid
dispersions composed of a hydrophobic drug and a hydrophilic polymer following exposure …

The thermal behavior of binary mixtures of paracetamol and a polymeric excipient
(microcrystalline cellulose, hydroxypropylmethylcellulose and cross-linked poly …