[HTML][HTML] The dual role of autophagy in cancer development and a therapeutic strategy for cancer by targeting autophagy

CW Yun, J Jeon, G Go, JH Lee, SH Lee - International journal of …, 2020 - mdpi.com
Autophagy is a delicate intracellular degradation process that occurs due to diverse stressful
conditions, including the accumulation of damaged proteins and organelles as well as …

[HTML][HTML] The roles of autophagy in cancer

CW Yun, SH Lee - International journal of molecular sciences, 2018 - mdpi.com
Autophagy is an intracellular degradative process that occurs under several stressful
conditions, including organelle damage, the presence of abnormal proteins, and nutrient …

[HTML][HTML] Molecular mechanisms of autophagy in cancer development, progression, and therapy

VAM Vitto, S Bianchin, AA Zolondick, G Pellielo… - Biomedicines, 2022 - mdpi.com
Autophagy is an evolutionarily conserved and tightly regulated process that plays an
important role in maintaining cellular homeostasis. It involves regulation of various genes …

[HTML][HTML] Autophagy in cancer

X Zhi, Q Zhong - F1000prime reports, 2015 - ncbi.nlm.nih.gov
Autophagy is a catabolic degradation process in which cellular proteins and organelles are
engulfed by double-membrane autophagosomes and degraded in lysosomes. Autophagy …

Autophagy as a molecular target for cancer treatment

NM Kocaturk, Y Akkoc, C Kig, O Bayraktar… - European Journal of …, 2019 - Elsevier
Autophagy is an evolutionarily conserved catabolic mechanism, by which eukaryotic cells
recycle or degrades internal constituents through membrane-trafficking pathway. Thus …

[HTML][HTML] Is targeting autophagy mechanism in cancer a good approach? The possible double-edge sword effect

SM Lim, EA Mohamad Hanif, SF Chin - Cell & Bioscience, 2021 - Springer
Autophagy is a conserved cellular process required to maintain homeostasis. The hallmark
of autophagy is the formation of a phagophore that engulfs cytosolic materials for …

[HTML][HTML] Autophagy regulation in cancer development and therapy

EJ White, V Martin, JL Liu, SR Klein, S Piya… - American journal of …, 2011 - ncbi.nlm.nih.gov
Autophagy is a cellular process to degrade long-lived or malfunctioning proteins and
obsolete or damaged organelles. It maintains cellular homeostasis and helps cells survive …

[HTML][HTML] Role and regulation of autophagy in cancer

R Rakesh, LC PriyaDharshini, KM Sakthivel… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Autophagy is an intracellular self-degradative mechanism which responds to cellular
conditions like stress or starvation and plays a key role in regulating cell metabolism, energy …

[HTML][HTML] Understanding the role of autophagy in cancer formation and progression is a real opportunity to treat and cure human cancers

S Patergnani, S Missiroli, G Morciano, M Perrone… - Cancers, 2021 - mdpi.com
Simple Summary The modulation of autophagy represents a potential therapeutic strategy
for cancer. More than one hundred clinical trials have been conducted or are ongoing to …

Autophagy paradox of cancer: Role, regulation, and duality

AK Verma, PS Bharti, S Rafat, D Bhatt… - Oxidative Medicine …, 2021 - Wiley Online Library
Autophagy, a catabolic process, degrades damaged and defective cellular materials through
lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily …