In 1934, Oppenheimer and Kugel established the eponym of Werner syndrome13. This
disease, which occurs with equal frequency in males and females, usually becomes …

Werner syndrome is a rare autosomal recessive disorder characterized by clinical signs of
premature aging, short stature, scleroderma-like skin changes, endocrine abnormalities …

Epidemiology Patients with WS have been identified worldwide, with the largest number in
Japan (1017). Estimates of the frequency or prevalence of WS, obtained from casecounting …

Osteosarcomatous transformation in fibrous dysplasia is unusual. The incidence is
increased in patients with concomitant Mazabraud's syndrome and McCune-Albright …

There are 2 types of hereditary polyposis diseases: adenomatous—which includes familial
adenomatous polyposis (FAP)—and hamartomatous. Gardner's syndrome (OMIM 175100) …

This article describes the clinical and pathologic features of four unusual bone tumors. Three
were congenital or most likely so; the fourth, detected at age 1 year, was probably of …

REPORT OF CASE Clinical History: DS, a girl I7 years of age, was first admitted to the Alfred
Hospital in March, I936. In December, I934, she had injured the left lower limb at play; it had …

Osteogenic sarcoma comprises less than 0.5 per cent of all cancers. Two brothers were
recently seen who were diagnosed as having osteogenic sarcoma approximately 28 months …

We report a 16-year-old growth deficient boy with craniosynostosis, radial hypoplasia and
hypoplastic thumbs. These findings are consistent with the autosomal recessively inherited …

Here, we report on a patient with Muenke syndrome with an osteochondroma, which to our
knowledge, has not been previously recorded. The syndrome consists of coronal synostosis …