Review on metal-based nanoparticles: role of reactive oxygen species in renal toxicity
The rapidly emerging field of nanotechnology has offered innovative discoveries. Due to a
wide variety of nanotechnology applications in the industrial, medical, and consumptive …
wide variety of nanotechnology applications in the industrial, medical, and consumptive …
Nanomedicines for renal disease: current status and future applications
N Kamaly, JC He, DA Ausiello… - Nature Reviews …, 2016 - nature.com
Abstract Treatment and management of kidney disease currently presents an enormous
global burden, and the application of nanotechnology principles to renal disease therapy …
global burden, and the application of nanotechnology principles to renal disease therapy …
ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule
D Liu, G Shu, F Jin, J Qi, X Xu, Y Du, H Yu, J Wang… - Science …, 2020 - science.org
The development of drugs with rapid distribution in the kidney and long-term retention in the
renal tubule is a breakthrough for enhanced treatment of acute kidney injury (AKI). Here, l …
renal tubule is a breakthrough for enhanced treatment of acute kidney injury (AKI). Here, l …
Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI
D Zou, R Ganugula, M Arora… - American Journal …, 2019 - journals.physiology.org
The popular anticancer drug cisplatin causes many adverse side effects, the most serious of
which is acute kidney injury (AKI). Emerging evidence from laboratory and clinical studies …
which is acute kidney injury (AKI). Emerging evidence from laboratory and clinical studies …
Oral administration of Si-based agent attenuates oxidative stress and ischemia-reperfusion injury in a rat model: a novel hydrogen administration method
M Kawamura, R Imamura, Y Kobayashi… - Frontiers in …, 2020 - frontiersin.org
Organ ischemia-reperfusion injury (IRI), which is unavoidable in kidney transplantation,
induces the formation of reactive oxygen species and causes organ damage. Although the …
induces the formation of reactive oxygen species and causes organ damage. Although the …
Physiological principles underlying the kidney targeting of renal nanomedicines
Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …
considerable morbidity and mortality, highlighting a need for new therapeutic options …
Restoring cellular calcium homeostasis to rescue ER stress by 1, 2-bis (2-aminophenoxy) ethane-N, N, N′, N′-tetraacetic acid acetoxymethyl ester-loaded lipid …
J Zhang, J Yan, Y Wang, H Liu, X Sun, Y Gu, L Yu… - Chinese Chemical …, 2024 - Elsevier
Early pathogenesis of ischemia-reperfusion (I/R)-induced acute kidney injury (AKI) is
dominated by intracellular calcium overload, which induces oxidative stress, intracellular …
dominated by intracellular calcium overload, which induces oxidative stress, intracellular …
An Ultrasmall RuO2 Nanozyme Exhibiting Multienzyme-like Activity for the Prevention of Acute Kidney Injury
Oxidative stress induced by reactive oxygen species (ROS) is one of the major pathological
mechanisms of acute kidney injury (AKI). Inorganic nanomaterial-mediated antioxidant …
mechanisms of acute kidney injury (AKI). Inorganic nanomaterial-mediated antioxidant …
[HTML][HTML] Unveiling drug induced nephrotoxicity using novel biomarkers and cutting-edge preventive strategies
Drug-induced nephrotoxicity is still a significant obstacle in pharmacotherapy of various
diseases and it accounts for around 25% of serious side-effects reported after drug …
diseases and it accounts for around 25% of serious side-effects reported after drug …
Nanotechnology, nanomedicine, and the kidney
The kidneys are vital organs performing several essential functions. Their primary function is
the filtration of blood and the removal of metabolic waste products as well as fluid …
the filtration of blood and the removal of metabolic waste products as well as fluid …