Infection with human T-cell lymphotrophic virus-I (HTLV-I) is now a global epidemic, affecting
10 million to 20 million people. This virus has been linked to life-threatening, incurable …

Epidemiologic aspects of human T-lymphotropic virus type I (HTLV-I) infection have been
thoroughly studied over the course of approximately 25 years since its first description. The …

Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …

Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a
proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes …

The human T-cell leukemia virus type 1 (HTLV-1), identified as the first human oncogenic
retrovirus 30 years ago, is not an ubiquitous virus. HTLV-1 is present throughout the world …

Human T-lymphotropic virus type II (HTLV-II) is a human retrovirus which is endemic in
Amerindian and pygmy tribes. Molecular subtypes show geographic segregation consistent …

It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …

Human T-cell leukemia virus type 1 (HTLV-1), the first human retrovirus to be discovered, is
present in diverse regions of the world, where its infection is usually neglected in health care …

Highlights•Molecular mechanisms of HTLV-1 oncogenesis.•Innate and acquired immune
response to HTLV-1.•Clonality of HTLV-1 in vivo.•We bring together the host and viral factors …

Abstract HTLV-1 and HTLV-2 are highly related complex retroviruses that have been studied
intensely for nearly three decades because of their association with neoplasia …