Engineered Cas9 variant tools expand targeting scope of genome and base editing in rice -
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CRISPR-Cas9 systems have been widely used in animals and plants for genome editing,
epigenetic modification, etc.(Cong et al., 2013; Hilton et al., 2015). However, the accurate …

The CRISPR/Cas9 system has emerged as a versatile molecular tool for genome editing in
various organisms, including plants. In this system, the specificity of Cas9-directed DNA …

The CRISPR/Cas system has rapidly become the preferred tool for genome engineering in
various organisms due to high efficiency, specificity, simplicity and versatility. Currently …

Background Application of the CRISPR/Cas9 system or its derived base editors enables
targeted genome modification, thereby providing a programmable tool to exploit gene …

CRISPR‐Cas12a enables efficient biallelic gene targeting in rice - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

Genome editing technologies enable precise modifications of DNA sequences in vivo and
offer great promise for crop improvement. CRISPR/Cas9 (Clustered Regularly Interspaced …

Background Targeting specificity has been a barrier to applying genome editing systems in
functional genomics, precise medicine and plant breeding. In plants, only limited studies …

PAM‐relaxed Cas9 nucleases, cytosine base editors and adenine base editors are
promising tools for precise genome editing in plants. However, their genome‐wide off‐target …

CRISPR/Cas9 (clustered regularly interspaced short palindromic repeats/CRISPR-
associated Cas9) has been widely used in genome editing in a variety of organisms …