[PDF][PDF] 2′-岩藻糖基乳糖的生物合成菌株构建及发酵条件研究

李晨晨, 李梦丽, 江波, 张涛 - 食品与发酵工业, 2021 - sf1970.cnif.cn
岩藻糖基乳糖(2′-fucosyllactose, 2′-FL) 可作为益生元添加到婴幼儿配方奶粉中,
对婴幼儿肠道菌群和免疫系统的发育至关重要. 通过共表达L-岩藻糖激酶/GDP-L …

2'‐岩藻糖基乳糖功能及其微生物生产菌种构建研究进展.

刘琳, 赵藤, 高俊哲, 李俊众, 孙雪… - Food Research & …, 2024 - search.ebscohost.com
2′⁃ 岩藻糖基乳糖(2′⁃ fucosyllactose, 2′⁃ FL) 在人乳寡糖中含量最高, 占比可达30%.
2′⁃ FL 能够有效促进婴儿大脑发育, 提高婴儿免疫力, 对青少年, 成年人, 老年人也大有裨益 …

乳酸乳球菌生产2'-岩藻糖基乳糖的途径构建及发酵培养基优化.

程亚楠, 张文聪, 周圆, 孙雪, 李玉… - Biotechnology …, 2023 - search.ebscohost.com
2'-岩藻糖基乳糖(2'-fucosyllactose, 2'-FL) 是一种含量最丰富的人乳寡糖, 微生物全细胞合成是
生产2'-FL 的重要方法. 乳酸乳球菌(Lactococcus lactis) 作为一种可直接用于乳制品的食品级 …

Strain development and fermentation optimization for biosynthesis of 2'-fucosyllactose.

C Li, M Li, B Jiang, T Zhang - 2021 - cabidigitallibrary.org
As a kind of prebiotics, 2'-fucosyllactose (2'-FL) can be added to infant formula, and is
essential for the development of the intestinal flora and immune system of infants. The …

Improved production of 2′-fucosyllactose in engineered Escherichia coli by expressing putative α-1, 2-fucosyltransferase, WcfB from Bacteroides fragilis

YW Chin, JY Kim, JH Kim, SM Jung, JH Seo - Journal of biotechnology, 2017 - Elsevier
Fucosyllactose (2-FL) is one of most abundant oligosaccharides in human milk, which is
involved in many biological functions for infant health. Since 2-FL has a great potential in …

Simultaneous production of 2′‐fucosyllactose and difucosyllactose by engineered Escherichia coli with high secretion efficiency

HJ Lee, DJ Shin, K Han, YW Chin, JP Park… - Biotechnology …, 2022 - Wiley Online Library
Abstract Background and aim Difucosyllactose (Di‐FL) has strong antimicrobial activity
against various pathogens, including group B Streptococcus, identified as the leading cause …

Improved production of 2′-fucosyllactose in engineered Saccharomyces cerevisiae expressing a putative α-1, 2-fucosyltransferase from Bacillus cereus

M Xu, X Meng, W Zhang, Y Shen, W Liu - Microbial Cell Factories, 2021 - Springer
Abstract Background 2′-fucosyllactose (2′-FL) is one of the most abundant
oligosaccharides in human milk. It constitutes an authorized functional additive to improve …

Synthesis of 2′-fucosyllactose from apple pomace–derived xyloglucan oligosaccharides by an α-L-fucosidase from Pedobacter sp. CAU209

R Shi, S Yang, N Wang, Q Yan, X Yan… - Applied Microbiology and …, 2023 - Springer
Fucosyllactose (2′-FL) is known for its ability to provide various health benefits to infants,
such as gut maturation, pathogen resistance, improved immunity, and nervous system …

[引用][C] 2′-岩藻糖基乳糖的微生物合成研究进展

瓮茹茹, 卫鑫慧, 李浩正, 路福平, 李玉 - 食品科学, 2021

[引用][C] 地杆菌α-L-岩藻糖苷酶的分子改造及其在合成2'-岩藻糖基乳糖中的应用

史然, 张登娅, 谷懿寰, 江正强, 杨绍青 - 食品科学, 2021