Lack of P2X receptor mediated currents in astrocytes and GluR type glial cells of the hippocampal CA1 region

R Jabs, K Matthias, A Grote, M Grauer, G Seifert… - Glia, 2007 - Wiley Online Library
Purinergic signalling plays a major role in intercellular communication between neurons and
glial cells. Glial cells express metabotropic receptors for ATP and adenosine, the latter being …

Modulation of heteromeric P2X1/5 receptors by phosphoinositides in astrocytes depends on the P2X1 subunit

AR Ase, LP Bernier, D Blais, Y Pankratov… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 113, 1676–1684. Abstract Purinergic signaling is critical for neuron‐
glia communication. Glial cells participate in synaptic transmission and express …

P2X1 and P2X5 subunits form the functional P2X receptor in mouse cortical astrocytes

U Lalo, Y Pankratov, SP Wichert… - Journal of …, 2008 - Soc Neuroscience
ATP plays an important role in signal transduction between neuronal and glial circuits and
within glial networks. Here we describe currents activated by ATP in astrocytes acutely …

Functional P2X7 receptors at cultured hippocampal astrocytes but not neurons

P Rubini, G Pagel, S Mehri, P Marquardt… - Naunyn-Schmiedeberg's …, 2014 - Springer
P2X7 receptors have been suggested to be located both on neurons and astrocytes of the
central and peripheral nervous systems. In the present Ca 2+-imaging and patch-clamp …

Distribution of P2X receptors on astrocytes in juvenile rat hippocampus

M Kukley, JA Barden, C Steinhäuser, R Jabs - Glia, 2001 - Wiley Online Library
Recent evidence suggested that ATP acting via ionotropic (P2X) and metabotropic (P2Y)
purinergic receptors might be involved in signaling between glial cells and within glial …

Astrocytic rather than neuronal P2X7 receptors modulate the function of the tri-synaptic network in the rodent hippocampus

MT Khan, J Deussing, Y Tang, P Illes - Brain research bulletin, 2019 - Elsevier
Whole-cell patch clamp recordings demonstrated that in the dentate gyrus (DG) as well as in
the CA3 area of mouse hippocampal slices the prototypic P2X7 receptor (R) agonist …

Electrophysiological classification of P2X7 receptors in rat cultured neocortical astroglia

W Nörenberg, J Schunk, W Fischer… - British journal of …, 2010 - Wiley Online Library
Background and purpose: P2X7 receptors are ATP‐gated cation channels mediating
important functions in microglial cells, such as the release of cytokines and phagocytosis …

Rodent Cortical Astroglia Express In Situ Functional P2X7 Receptors Sensing Pathologically High ATP Concentrations

JF Oliveira, T Riedel, A Leichsenring, C Heine… - Cerebral …, 2011 - academic.oup.com
ATP is an important neuronal and astroglial signaling molecule in the brain. In the present
study, brain slices were prepared from the prefrontal cortex (PFC) of Wistar rats and 2 lines …

Increase of intracellular Ca2+ by P2X and P2Y receptor-subtypes in cultured cortical astroglia of the rat

W Fischer, K Appelt, M Grohmann, H Franke… - Neuroscience, 2009 - Elsevier
Astrocytes express purinergic receptors that are involved in glial–neuronal cell
communication. Experiments were conducted to characterize the expression of functional …

Lack of ATP-evoked GABA and glutamate release in the hippocampus of P2X7 receptor−/− mice

L Papp, ES Vizi, B Sperlágh - Neuroreport, 2004 - journals.lww.com
In this study we revealed the participation of P2X 7 receptors in the modulation of electrical
stimulation and ATP-evoked GABA and glutamate release from mouse hippocampal slices …