Osteosarcoma (OS) is the most frequent primary malignant bone tumor. Ferroptosis, a form
of regulated cell death, is a key tumor suppression mechanism. Although methionine …

Osteosarcoma (OS) is the most commonly diagnosed bone tumor in young people with poor
prognosis. At present, the mechanisms underlying tumorigenesis in OS are not well …

Doxorubicin and platinum are widely used in the frontline treatment of osteosarcoma, but
resistance to chemotherapy limits its curative effect. Here, we have identified that METTL1 …

Background Ferroptosis, a unique form of nonapoptotic-regulated cell death caused by
overwhelming lipid peroxidation, represents an emerging tumor suppression mechanism …

Objective Ferroptosis has been defined as a novel form of regulated cell death characterized
by iron‐dependent lipid peroxidation. Manganese has been used to induce ferroptosis in …

Ferroptosis is a kind of regulatory necrosis caused by phospholipid iron-dependent
peroxidation. MiRNAs are known to play key roles in diverse biological functions. However …

Ferroptosis is a regulated form of cell death driven by small molecules or conditions that
induce lipid-based reactive oxygen species (ROS) accumulation. This form of iron …

Background: Emerging evidence suggests that long noncoding RNAs (lncRNAs) play an
important role in the progression of multiple human cancers including breast cancer. In this …

Ferroptosis is a recently recognized form of regulated cell death driven by lipid‐based
reactive oxygen species (ROS) accumulation. However, the molecular mechanisms of …

Background Ferroptosis is a newly generated regulatory cell death promoted by the
accumulated lipid-based reactive oxygen species (ROS). Solute carrier family 7 member 11 …