MicroRNA-25–5p counteracts oxidized LDL-induced pathological changes by targeting neuronal growth regulator 1 (NEGR1) in human brain micro-vessel endothelial …

Q Zhang, C Liu, Q Li, J Li, Y Wu, J Liu - Biochimie, 2019 - Elsevier
Abstract MicroRNA-25–5p (miR-25–5p) may be involved in the pathogenesis and processes
of vascular diseases. The aim of this study was to investigate the role of miR-25–5p in …

[HTML][HTML] MicroRNA‑329‑3p alleviates high glucose‑induced endothelial cell injury via inhibition of the TLR4/TRAF6/NF‑κB signaling pathway

G Song, L Li, Y Yang - Experimental and Therapeutic …, 2021 - spandidos-publications.com
The aim of the current study was to determine the expression of microRNA (miRNA/miR)‑
329‑3p in patients with type 2 diabetes mellitus (T2DM) and to investigate the effect of miR …

MicroRNA‐182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas

YQ Wang, RD Guo, RM Guo… - Journal of cellular …, 2013 - Wiley Online Library
As an important tumor suppressor, programmed cell death 4 (PDCD4) influences
transcription and translation of multiple genes, and modulates different signal transduction …

miR‐149 alleviates ox‐LDL‐induced endothelial cell injury by promoting autophagy through Akt/mTOR pathway

Z Zhu, J Li, R Tong, X Zhang… - Cardiology Research and …, 2021 - Wiley Online Library
Background. Atherosclerosis is a chronic process that takes place in the vascular wall and
causes various cardiovascular diseases (CVDs). Micro‐RNA‐149 (miR‐149) mediates …

MicroRNA‐497 functions as an inflammatory suppressor via targeting DDX3Y and modulating toll‐like receptor 4/NF‐κB in cigarette smoke extract‐stimulated human …

R Jia, XF Zhao - The journal of gene medicine, 2020 - Wiley Online Library
Background We aimed to investigate the biological effect of miR‐497 in cigarette smoke
extract (CSE)‐damaged human bronchial epithelial (HBE) cells and the underlying …

[HTML][HTML] Ischemic postconditioning-regulated miR-499 protects the rat heart against ischemia/reperfusion injury by inhibiting apoptosis through PDCD4

J Zhu, K Yao, Q Wang, J Guo, H Shi, L Ma… - Cellular Physiology and …, 2016 - karger.com
Background: Here, we determined miR-499 involvement in the protective effect of ischemic
postconditioning (IPC) against myocardial ischemia/reperfusion (I/R) injury and identified the …

miR‑98 inhibits cell proliferation and induces cell apoptosis by targeting MAPK6 in HUVECs

C Hu, S Huang, F Wu, H Ding - Experimental and …, 2018 - spandidos-publications.com
The aim of current study was to explore the role of microRNA (miR)‑98 in atherosclerosis.
Human vascular endothelial cells (HVECs) were isolated from the peripheral blood of …

MicroRNA-125a-5p alleviates the deleterious effects of ox-LDL on multiple functions of human brain microvessel endothelial cells

Q Pan, X Liao, H Liu, Y Wang, Y Chen… - … of Physiology-Cell …, 2017 - journals.physiology.org
MicroRNA-125a-5p (miR-125a-5p) could participate in the pathogenesis of vascular
diseases. In this study, we investigated the role of miR-125a-5p in oxidized low-density …

Downregulated miRNA-26a-5p induces the apoptosis of endothelial cells in coronary heart disease by inhibiting PI3K/AKT pathway.

R Jing, TY LONG, W PAN… - European Review for …, 2019 - search.ebscohost.com
OBJECTIVE: Multiple microRNAs (miRNAs) are abnormally expressed in endothelial cells
during the occurrence of coronary artery disease (CAD). Previous researches have …

Effect of microRNA‑144‑5p on the proliferation, invasion and migration of human umbilical vein endothelial cells by targeting SMAD1

W Fu, Z Liu, J Zhang, Y Shi… - Experimental and …, 2020 - spandidos-publications.com
Atherosclerosis is a multifactorial chronic disease that is a major cause of death and injury
worldwide. Apoptosis of endothelial cells (ECs) serves an important role in the occurrence …