Background and aims MicroRNA (miR)-146 is a key regulator of inflammation, endothelial
activation and atherosclerosis. This study sought to define its potential role for the …

Hypertension is a major public health problem among the aging population worldwide. It
causes cardiac remodeling, including hypertrophy and interstitial fibrosis, which leads to …

Background. The endothelium is the first line of defence against harmful microenvironment
risks, and microRNAs (miRNAs) involved in vascular inflammation may be promising …

Abstract Paeonol (2'-hydroxy-4'-methoxyacetophenone) is an active component isolated
from the root of Paeonia Suffruticosa Andrews. We previously found that paeonol inhibited …

Ischemia–reperfusion injury (IRI) is a major cause of cardiac damage following various
pathological processes, such as free radical damage and cell apoptosis. This study aims to …

Plenty of microRNAs have been identified as critical mediators in atherosclerosis
progression, which is still a great threat to human health. Oxidative stress and inflammation …

Contrast medium (CM) is widely used in cardiac catheterization; however, it may induce
acute kidney injury or renal failure, although the underlying mechanism remains to be …

OBJECTIVE: The current study investigates the effect of the innovative phosphorothioate
modified backbone locked nucleic acid (LNA) of microRNA-103 (miR-103) specifically …

Breast cancer (BC) is the leading cause of cancer‑associated mortality among women
worldwide, with a poor 5‑year survival rate, particularly among patients with metastatic BC …

The balance between proliferation and apoptosis of vascular smooth muscle cells (VSMCs)
plays a critical role in the initiation of atherosclerosis. LncRNA-MEG3 is involved in the …