Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens

CA Owesson‐White, MF Roitman… - Journal of …, 2012 - Wiley Online Library
J. Neurochem.(2012) 121, 252–262. Abstract Mesolimbic dopamine neurons fire in both
tonic and phasic modes resulting in detectable extracellular levels of dopamine in the …

Dynamics of rapid dopamine release in the nucleus accumbens during goal-directed behaviors for cocaine versus natural rewards

CM Cameron, RM Wightman, RM Carelli - Neuropharmacology, 2014 - Elsevier
Electrophysiological studies show that distinct subsets of nucleus accumbens (NAc) neurons
differentially encode information about goal-directed behaviors for intravenous cocaine …

Real‐time assessments of dopamine function during behavior: single‐unit recording, iontophoresis, and fast‐scan cyclic voltammetry in awake, unrestrained rats

GV Rebec - Alcoholism: Clinical and Experimental Research, 1998 - Wiley Online Library
Although ample evidence implicates the dopamine (DA) projection to the neostriatum and
nucleus accumbens in motor and motivational processes, relatively little information is …

Phasic inhibition of dopamine uptake in nucleus accumbens induced by intravenous cocaine in freely behaving rats

EA Kiyatkin, DE Kiyatkin, GV Rebec - Neuroscience, 2000 - Elsevier
A new approach combining fast-scan cyclic voltammetry with iontophoretic dopamine
delivery was used in freely behaving rats to evaluate the time-course of dopamine uptake …

Sensitization of midbrain dopamine neuron reactivity and the self-administration of psychomotor stimulant drugs

P Vezina - Neuroscience & Biobehavioral Reviews, 2004 - Elsevier
Psychostimulant drugs like amphetamine are readily self-administered by humans and
laboratory animals by virtue of their actions on dopamine (DA) neurons in the midbrain …

Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats

R Ito, JW Dalley, SR Howes, TW Robbins… - Journal of …, 2000 - Soc Neuroscience
The dopaminergic innervation of the nucleus accumbens is generally agreed to mediate the
primary reinforcing and locomotor effects of psychostimulants, but there is less consensus …

Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats

HO Pettit, A Ettenberg, FE Bloom, GF Koob - Psychopharmacology, 1984 - Springer
The hypothesis that separate neural systems mediate the reinforcing properties of opioid
and psychomotor stimulant drugs was tested by examining the role of mesolimbic dopamine …

Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: an in vivo electrochemical study

EA Kiyatkin, EA Stein - Neuroscience, 1995 - Elsevier
High-speed chronoamperometry with Nafion-coated monoamine-sensitive carbon fiber
electrodes was used to estimate changes in extracellular dopamine concentration in the …

The tonic/phasic model of dopamine system regulation and its implications for understanding alcohol and psychostimulant craving

AA Grace - Addiction, 2000 - Wiley Online Library
All drugs of abuse have been shown to act either directly or indirectly by increasing
dopamine neurotransmission within the limbic system. Thus, alcohol has been shown to …

[HTML][HTML] Rapid dopamine dynamics in the accumbens core and shell: learning and action

MP Saddoris, JA Sugam, F Cacciapaglia… - Frontiers in bioscience …, 2013 - ncbi.nlm.nih.gov
The catecholamine dopamine (DA) has been implicated in a host of neural processes as
diverse as schizophrenia, parkinsonism and reward encoding. Importantly, these distinct …