Capsaicin is the active compound responsible for the pungency of hot chilli. Research has
discovered its ability to desensitize peripheral nociceptive fibers which is useful in treating …

There is a “painfully” absent chapter in pharmacological textbooks, which could be
entitled:“Drugs acting on sensory neurons” or “Sensory neuron-blocking analgesics.” For …

Capsaicin, the pungent ingredient of red pepper has become not only a “hot” topic in
neuroscience but its new target-related unique actions have opened the door for the drug …

BACKGROUND 0002) The vanilloid receptor 1 (VR1) is the molecular target of capsaicin,
the active ingredient in hot pepperS. Julius et al. reported the molecular cloning of VR1 …

Pain is not only an obnoxious sensation, but also a complex sensory process essential for
survival experienced due to activation nociceptors. Many herbal medicines have been used …

A large number of pharmacological studies have used capsaicin as a tool to activate many
physiological systems, with an emphasis on pain research but also including functions such …

Capsaicin, the pungent principle in chilli peppers has become a promising molecule for the
development of a new generation of analgesic-anti-inflammatory agents with a target …

This work will, in addition to describing the aromatic basis of capsaicin, elucidate its
mechanism of action through a positive inhibition of the nerve conduction, which ultimately …

Abstract Purpose of Review Capsaicin is a natural substance used to treat neuropathic pain
because of its ability to be used in a more direct form on patients and efficiently treat their …