[HTML][HTML] IHF stabilizes pathogenicity island I of uropathogenic Escherichia coli strain 536 by attenuating integrase I promoter activity

M Chittò, M Berger, P Berger, L Klotz, P Dröge… - Scientific Reports, 2020 - nature.com
Pathogenicity islands (PAIs) represent horizontally acquired chromosomal regions and
encode their cognate integrase, which mediates chromosomal integration and excision of …

Role of pathogenicity island‐associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536

B Hochhut, C Wilde, G Balling… - Molecular …, 2006 - Wiley Online Library
The genome of uropathogenic Escherichia coli isolate 536 contains five well‐characterized
pathogenicity islands (PAIs) encoding key virulence factors of this strain. Except PAI IV536 …

Delineation of the recombination sites necessary for integration of pathogenicity islands II and III into the Escherichia coli 536 chromosome

C Wilde, D Mazel, B Hochhut… - Molecular …, 2008 - Wiley Online Library
In uropathogenic Escherichia coli strain 536, six pathogenicity islands (PAIs) encode key
virulence factors. All PAIs except PAI IV536 are flanked by direct repeats and four of them …

Pathogenicity island integrase cross‐talk: a potential new tool for virulence modulation

JM Manson, MS Gilmore - Molecular microbiology, 2006 - Wiley Online Library
Instability and excision of pathogenicity islands (PAIs) have already been described in
Escherichia coli 536. In this edition of Molecular Microbiology, Bianca Hochhut and …

Pathogenicity island cross talk mediated by recombination directionality factors facilitates excision from the chromosome

MR Carpenter, S Rozovsky, EF Boyd - Journal of bacteriology, 2016 - Am Soc Microbiol
Pathogenicity islands (PAIs) are mobile integrated genetic elements (MIGEs) that contain a
diverse range of virulence factors and are essential in the evolution of pathogenic bacteria …

[HTML][HTML] Sub-Inhibitory concentrations of SOS-Response inducing antibiotics stimulate integrase expression and excision of pathogenicity islands in uropathogenic …

M Chittò, M Berger, L Klotz, U Dobrindt - International Journal of Medical …, 2020 - Elsevier
Urinary tract infections are one of the most common bacterial infections and a major public
health problem. The predominant causative agents are uropathogenic Escherichia coli …

Instability of Pathogenicity Islands in Uropathogenic Escherichia coli 536

B Middendorf, B Hochhut, K Leipold… - Journal of …, 2004 - Am Soc Microbiol
The uropathogenic Escherichia coli strain 536 carries at least five genetic elements on its
chromosome that meet all criteria characteristic of pathogenicity islands (PAIs). One main …

Multiple Insertional Events, Restricted by the Genetic Background, Have Led to Acquisition of Pathogenicity Island IIJ96-Like Domains among Escherichia coli …

P Bidet, S Bonacorsi, O Clermont… - Infection and …, 2005 - Am Soc Microbiol
We investigated the dissemination of pathogenicity island (PAI) IIJ96-like elements (hra, hly,
cnf1, and pap) among 455 Escherichia coli isolates from children and adults with urinary …

Dichotomy in the evolution of pathogenicity island and bacteriophage encoded integrases from pathogenic Escherichia coli strains

MG Napolitano, S Almagro-Moreno, EF Boyd - Infection, Genetics and …, 2011 - Elsevier
The evolutionary histories of mobile and integrative genetic elements (MIGEs), key factors in
the emergence of pathogenic bacteria, remain obscure due to their widespread distribution …

Identification and characterization of a phase-variable element that regulates the autotransporter UpaE in uropathogenic Escherichia coli

EJ Battaglioli, KGK Goh, TS Atruktsang, K Schwartz… - MBio, 2018 - Am Soc Microbiol
Uropathogenic Escherichia coli (UPEC) is the most common etiologic agent of
uncomplicated urinary tract infection (UTI). An important mechanism of gene regulation in …