Ramipril blunts glycerol-induced acute renal failure in rats through its antiapoptosis, anti-inflammatory, antioxidant, and renin-inhibiting properties

AA Adedapo, ER Osaretin, OO Falayi… - Journal of Basic and …, 2021 - degruyter.com
Objectives Acute kidney injury (AKI) is a malady with a sudden onset resulting in buildup of
waste matters in the body, but a specific cure hasn't been found as a lasting solution to AKI …

Protective effect of quinacrine against glycerol-induced acute kidney injury in rats

AK Al Asmari, KT Al Sadoon, AA Obaid… - BMC nephrology, 2017 - Springer
Background Acute kidney injury (AKI) is a serious clinical problem with high rate of mortality
and morbidity. Currently used prophylactic and therapeutic strategies to address AKI are …

Diacerein protects against glycerol-induced acute kidney injury: modulating oxidative stress, inflammation, apoptosis and necroptosis

RN Abd-Ellatif, II Hegab, MM Atef, MT Sadek… - Chemico-biological …, 2019 - Elsevier
Necroptosis is suggested to have an important role in the pathogenesis of rhabdomyolysis
induced acute kidney injury (AKI). In this study, the renoprotective effect of diacerein on …

Luteolin attenuates glycerol-induced acute renal failure and cardiac complications through modulation of kim-1/NF-κB/Nrf2 signaling pathways

AA Oyagbemi, OA Adejumobi, TO Ajibade… - Journal of Dietary …, 2021 - Taylor & Francis
Acute renal failure (ARF) has been documented as a life-threatening disease with high
morbidity and mortality. We investigated the protective effect of Luteolin against ARF. In this …

Carvedilol, an antihypertensive drug with antioxidant properties, protects against glycerol-induced acute renal failure

D Singh, V Chander, K Chopra - American journal of nephrology, 2003 - karger.com
Background/Aims: The pathogenesis of glycerol-induced myoglobinuric acute renal failure
involves, among other causes, ischaemia, vascular congestion and reactive oxygen …

Oleuropein suppresses oxidative, inflammatory, and apoptotic responses following glycerol-induced acute kidney injury in rats

M Yin, N Jiang, L Guo, Z Ni, AY Al-Brakati, MS Othman… - Life sciences, 2019 - Elsevier
Aim Here, we evaluated the possible protective effects of oleuropein, the major phenolic
constituent in virgin olive oil against glycerol-induced acute kidney injury (AKI) in rats. Main …

Protective effect of anisodamine in rats with glycerol-induced acute kidney injury

Y Li, B Xu, R An, X Du, K Yu, J Sun, G Zhang, W Wang… - BMC nephrology, 2019 - Springer
Background Anisodamine is used for the treatment of reperfusion injury in various organs. In
this study, we investigated the effectiveness and mechanisms of action of anisodamine in …

[HTML][HTML] The preventive role of pioglitazone in glycerol-induced acute kidney injury in rats during two different treatment periods

R Mousleh, S Al Laham… - Iranian journal of medical …, 2018 - ncbi.nlm.nih.gov
Background Acute kidney injury is the most life-threatening complication of rhabdomyolysis.
Glycerol is commonly used to induce this injury. The aim was to investigate the …

Gastrodin pretreatment alleviates renal ischemia-reperfusion injury

Y Zheng, N Zhang, F Bai - Urologia Internationalis, 2022 - karger.com
Introduction: This study aimed to investigate the possible effect of gastrodin in renal
ischemia-reperfusion injury (IRI) and the mechanisms. Methods: Forty-eight male Sprague …

Valsartan prevents glycerol-induced acute kidney injury in male albino rats by downregulating TLR4 and NF-κB expression

X Sun, Q Luan, S Qiu - International journal of biological macromolecules, 2018 - Elsevier
In this study, the protective effect of valsartan against glycerol-induced acute kidney injury
(AKI) in male albino rats was investigated. Valsartan is used to treat high blood pressure and …