Pancreatic cancer is a rapidly progressing disease with a poor prognosis. We still have
many questions about the pathogenesis, early diagnosis and precise treatment of this …

We recently established organoid models from normal and neoplastic murine and human
pancreas tissues. These organoids exhibit ductal-and disease stage-specific characteristics …

Despite recent advances in the treatment of cancer, pancreatic ductal adenocarcinoma
(PDAC) still retains the worst survival rate of common malignancies. Late diagnosis and lack …

Pancreatic cancer is a highly lethal form of digestive malignancy that poses significant
health risks to individuals worldwide. Chemotherapy‐based comprehensive treatment is the …

Pancreatic ductal adenocarcinoma (PDA) is a highly lethal malignancy for which new
treatment and diagnostic approaches are urgently needed. For such breakthroughs to be …

Pancreatic cancer is one of the most lethal malignancies due to its late diagnosis and limited
response to treatment. Tractable methods to identify and interrogate pathways involved in …

Simple Summary Pancreatic cancer tissue is resistant to anticancer drugs because of its
complex microenvironment. Cancer-associated fibroblasts (CAFs) are an important source …

Background Pancreatic ductal adenocarcinoma has the lowest survival rate among all major
cancers and is the third leading cause of cancer-related mortality. The stagnant survival …

In recent years, the development of ex vivo organoid cultures has gained substantial
attention as a model to study regenerative medicine and diseases in several tissues …

Despite recent therapeutic advances, pancreatic ductal adenocarcinoma (PDAC) remains
one of the most aggressive malignancies, with remarkable resistance to treatment, poor …