Two forms of ghrelin, acylated and desacyl, circulate in plasma. Although acylation is
thought to be essential for ghrelin biological activities, recent studies have suggested that …

Ghrelin is a gastric peptide hormone that has an important role in appetite control and GH
release. Circulating ghrelin levels are inversely correlated with body mass index and …

Abstract Octanoylated ghrelin (1–28)(intact ghrelin) is rapidly and easily degraded to
desoctanoyl forms or smaller fragments (degraded ghrelin). Plasma levels of intact and …

Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat
stomach and is involved in a novel system for regulating GH release. Although previous …

Ghrelin is an acylated peptide with growth-hormonereleasing activity (1). It was first isolated
from rat and human stomach during the search for an endogenous ligand to the “orphan” G …

The effects of specific nutritional factors on ghrelin secretion have not been investigated in
humans. Therefore, we assessed ghrelin responses to a high-carbohydrate meal (1217 kcal …

Context: Ghrelin, an acylated peptide hormone secreted from the gut, regulates appetite and
metabolism. Elucidating its pattern of secretion in the fed and fasted states is important in the …

Ghrelin is a gastric hormone that exerts a stimulatory effect on appetite and fat accumulation.
Ser (3) octanoylation is regarded as a prerequisite for ghrelin biological activity, although …

Objective Ghrelin is an acylated peptide, whose octanoyl modification is essential for its
biological activities. Previous studies demonstrated that fasting plasma ghrelin levels were …

Ghrelin, a 28-amino acid peptide predominantly produced by the stomach, displays strong
GH-releasing activity mediated by the GH secretagogue (GHS)-receptor (GHS-R) type 1a at …