Mutations in the dystrophin gene lead to dystrophin deficiency, which is the cause of
Duchenne muscular dystrophy (DMD). This important discovery more than 10 years ago …

Duchenne muscular dystrophy (DMD) is a degenerative disorder of the skeletal muscle in
human and is caused by mutations in the dystrophin gene. Themdxmouse is a spontaneous …

Advances in the understanding of the genetic basis for Duchenne muscular dystrophy over
the past 4 years has led to the quick application of molecular diagnostics. More recently …

Background Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to
dystrophin loss. Full‐length Dp427 is the primary dystrophin isoform expressed in muscle …

The primary cause of Duchenne muscular dystrophy (DMD) is a mutation in the dystrophin
gene leading to the absence of the corresponding RNA transcript and protein. Absence of …

The muscular dystrophies are a heterogeneous group of genetically caused muscle
degenerative disorders. The Kunkel laboratory has had a longstanding research program …

Molecular genetics has transformed clinical concepts of Duchenne muscular dystrophy
(DMD) in several different ways.(1) The disease can now be defined as a myopathy due to …

Duchenne muscular dystrophy (DMD) is caused by mutations in the gene that encodes the
427‐kDa cytoskeletal protein dystrophin. Increased knowledge of the function of dystrophin …

Duchenne muscular dystrophy Page 1 Duchenne muscular dystrophy Jeffrey S. Chamberlain
University of Michigan Medical School, Ann Arbor, Michigan, USA Progress in understanding …

Duchenne muscular dystrophy (DMD) is caused by mutations that impair normal production
of dystrophin in muscle and brain tissues. The dystrophin gene is expressed at extremely …