Muscular dystrophies are a group of diseases that primarily affect skeletal muscle and are
characterized by progressive muscle wasting and weakness. Although these diseases have …

We report a 4-yr and 5-month-old boy with severe clinical features of an early-onset
Duchenne muscular dystrophy, who had a very short (110 kDa) dystrophin at the …

ABSTRACT Introduction Duchenne and Becker muscular dystrophies (DMD and BMD) are X‐
linked myopathies caused by mutations of the dystrophin gene. Methods Multiplex ligation …

A large variety of mutations in the dystrophin gene cause Duchenne and Becker muscular
dystrophies, diseases affecting predominantly the striated muscles (skeletal and cardiac) …

The complete dystrophin mRNA sequence has been analyzed in 20 Duchenne muscular
dystrophy and Becker muscular dystrophy patients. In 13 cases, deletions in mRNA were …

Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is
one of the most common single gene disorders found in the developed world. In this fourth …

Duchenne muscular dystrophy (DMD) is the most prevalent and severe form of human
muscular dystrophy. While clinical descriptions of DMD date back to the 1850's, over 100 …

In the course of a mutation search performed by muscle dystrophin transcript analysis in 72
Duchenne and Becker Muscular Dystrophies (DMD/BMD) patients without gross gene …

Muscle dystrophin mRNAs from Duchenne (DMD) and Becker (BMD) patients with internal
deletion of the DMD gene were quantitated and sequenced. In all cases (eight DMD and …

Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle wasting disease. The
disease is due to mutations in the DMD gene that encodes for a large intracellular protein …