Dystrophinopathies are X-linked muscle diseases caused by mutations in the large DMD
gene. The most common mutations are detected by standard diagnostic techniques …

ABSTRACT Introduction Duchenne and Becker muscular dystrophies (DMD and BMD) are X‐
linked myopathies caused by mutations of the dystrophin gene. Methods Multiplex ligation …

Duchenne muscular dystrophy (DMD), a severe and lethal condition, is caused by the
absence of muscle dystrophin. Therapeutic trials aiming at the amelioration of muscle …

Duchenne muscular dystrophy (DMD) is a dystrophin-deficient lethal muscle disease. To
date, the catastrophic muscle wasting phenotype has only been seen in dystrophin-deficient …

Duchenne Muscular Dystrophy, an inherited and progressive muscle wasting disease, is
one of the most common single gene disorders found in the developed world. In this fourth …

Aims New therapies for neuromuscular disorders are often mutation specific and require to
be studied in patient's cell cultures. In Duchenne muscular dystrophy (DMD) dystrophin …

Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle wasting disease. The
disease is due to mutations in the DMD gene that encodes for a large intracellular protein …

Females with Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD)
mutations rarely exhibit clinical symptoms from childhood, although potential mechanisms …

Duchenne/Becker muscular dystrophies are the most frequent inherited neuromuscular
diseases caused by mutations of the dystrophin gene. However, approximately 30% of …

Background Dystrophin is a rod-shaped cytoplasmic protein that provides sarcolemmal
stability as a structural link between the cytoskeleton and the extracellular matrix via the …