The microRNA-29 (miR-29) family is among the most abundantly expressed microRNA in
the pancreas and liver. Here, we investigated the function of miR-29 in glucose regulation …

The microRNA-29 family members miR-29a-3p, miR-29b-3p, and miR-29c-3p are
ubiquitously expressed and consistently increased in various tissues and cell types in …

Dysfunctional microRNA (miRNA) networks contribute to inappropriate responses following
pathological stress and are the underlying cause of several disease conditions. In …

Type 2 diabetes (T2D) is characterized by insulin resistance and increased hepatic glucose
production, yet the molecular mechanisms underlying these abnormalities are poorly …

MicroRNAs (miRNAs) are important posttranscriptional regulators of metabolism and energy
homeostasis. Dysregulation of certain miRNAs in the liver has been shown to contribute to …

Pancreatic β cell dysfunction contributes to the pathogenesis of type 2 diabetes. MiR-21 has
been shown to be induced in the islets of glucose intolerant patients and type 2 diabetic …

Chronically elevated levels of glucose impair pancreatic beta-cell function while inducing
beta-cell proliferation. MicroRNA-29a (miR-29a) levels are increased in several tissues in …

Metabolic diseases are characterized by the failure of regulatory genes or proteins to
effectively orchestrate specific pathways involved in the control of many biological …

MicroRNAs (miRNAs) are endogenous, noncoding, short, single-stranded RNAs that are
evolutionarily conserved and believed to play a role in controlling a variety of biological …

MicroRNAs have emerged as important regulators of glucose and lipid metabolism in
several tissues; however, their role in skeletal muscle remains poorly characterized. We …