Correlation of hMLH1 and HPP1 hypermethylation in gastric, but not in esophageal and cardiac adenocarcinoma
H Geddert, S Kiel, E Iskender, AR Florl… - … journal of cancer, 2004 - Wiley Online Library
Using methylation‐specific real‐time PCR, we determined the prevalence of aberrant
methylation in the mismatch repair gene hMLH1 and in the recently described HPP1 gene …
methylation in the mismatch repair gene hMLH1 and in the recently described HPP1 gene …
DNA mismatch repair gene methylation in gastric cancer in individuals from northern Brazil
E Moura Lima, M Ferreira Leal… - Biocell, 2008 - SciELO Argentina
Gastric cancer is one of the most common malignancies. DNA methylation is implicated in
DNA mismatch repair genes deficiency. In the present study, we evaluated the methylation …
DNA mismatch repair genes deficiency. In the present study, we evaluated the methylation …
Comprehensive analysis of promoter methylation and altered expression of hMLH1 in gastric cancer cell lines with microsatellite instability
Purpose: Aberrant methylation of the promoter CpG island of hMLH1 is associated with gene
silencing in colon cancer and gastric cancer with microsatellite instabilities (MSI). We …
silencing in colon cancer and gastric cancer with microsatellite instabilities (MSI). We …
Role of hMLH1 and E-cadherin promoter methylation in gastric cancer progression
Introduction Gastric cancer (GC) is one of the leading causes of cancer-related death in Iran.
Genome stability is one of the main genetic issues in cancer biology which is governed via …
Genome stability is one of the main genetic issues in cancer biology which is governed via …
Hypermethylation of the hMLH1 gene promoter in solitary and multiple gastric cancers with microsatellite instability
K Sakata, G Tamura, Y Endoh, K Ohmura… - British journal of …, 2002 - nature.com
Human cancers with a high frequency microsatellite instability phenotype develop due to
defects in DNA mismatch repair genes. Silencing of a DNA mismatch repair gene, hMLH1 …
defects in DNA mismatch repair genes. Silencing of a DNA mismatch repair gene, hMLH1 …
Hypermethylation of HPP1 Is Associated with hMLH1 Hypermethylation in Gastric Adenocarcinomas
DM Shibata, F Sato, Y Mori, K Perry, J Yin, S Wang… - Cancer research, 2002 - AACR
The HPP1 gene was initially discovered because of its frequent hypermethylation in
hyperplastic colon polyps, but it is also hypermethylated in colorectal adenomas and …
hyperplastic colon polyps, but it is also hypermethylated in colorectal adenomas and …
Hypermethylation of the hMLH1 Gene Promoter in Human Gastric Cancers with Microsatellite Instability
AS Fleisher, M Esteller, S Wang, G Tamura, H Suzuki… - Cancer research, 1999 - AACR
Human gastric carcinoma shows a higher prevalence of microsatellite instability (MSI) than
does any other type of sporadic human cancer. The reasons for this high frequency of MSI …
does any other type of sporadic human cancer. The reasons for this high frequency of MSI …
[HTML][HTML] Epigenetic silencing of the MLH1 promoter in relation to the development of gastric cancer and its use as a biomarker for patients with microsatellite instability …
G Hu, L Qin, X Zhang, G Ye, T Huang - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Human mutL homolog 1 (MLH1) promoter methylation was reported in
gastric cancer (GC). This study determined the clinicopathological, prognostic, and …
gastric cancer (GC). This study determined the clinicopathological, prognostic, and …
Methylation of the hMLH1 promoter but no hMLH1 mutations in sporadic gastric carcinomas with high‐level microsatellite instability
RAU Bevilacqua, AJG Simpson - International journal of cancer, 2000 - Wiley Online Library
Microsatellite instability (MSI) in tumors from patients with hereditary non‐polyposis
colorectal cancer (HNPCC) is caused by germline mutations in mismatch repair (MMR) …
colorectal cancer (HNPCC) is caused by germline mutations in mismatch repair (MMR) …