[11C] TMSX ([7-N-methyl-11C]-(E)-8-(3, 4, 5-trimethoxystyryl)-1, 3, 7-trimethylxanthine) is a
selective adenosine A2A receptor (A2AR) radioligand. In the central nervous system (CNS) …

Performance of two supervised cluster analysis (SVCA) algorithms for extracting reference
tissue curves was evaluated to improve quantification of dynamic (R)-[11C] PK11195 brain …

A metabolite corrected arterial input function is a prerequisite for quantification of positron
emission tomography (PET) data by compartmental analysis. This quantitative approach is …

This is the first study to report results from a noninvasive dual-tracer positron emission
tomography (PET) in humans not requiring arterial sampling, in which two radiotracers were …

Extraction of arterial input functions from dynamic brain scans may obviate the need for
arterial sampling and would increase the clinical applicability of quantitative PET studies …

The [18F] fluorodeoxyglucose ([18F] FDG) method for measuring brain metabolism has not
the wide clinical application that one might expect, partly because of its high cost and the …

In emission tomography, quantification of brain tracer uptake, metabolism or binding
requires knowledge of the cerebral input function. Traditionally, this is achieved with arterial …

Current PET datasets are becoming larger, thereby increasing the demand for fast and
reproducible processing pipelines. This paper presents a freely available, open source …

In quantitative dynamic PET studies, graphical analysis methods including the Gjedde–
Patlak plot, the Logan plot, and the relative equilibrium-based graphical plot (RE plot)(Zhou …

In hybrid magnetic resonance-positron emission tomography (MR-PET) studies with the
Siemens 3T MR-BrainPET scanner an instantaneous reduction of the PET sensitivity was …