OBJECTIVE: To quantify expression of progesterone receptor (PR) messenger RNA (mRNA)
isoforms in fetal membranes, and to determine whether these levels change in culture …

OBJECTIVE: The role of progesterone in the control of human parturition remains unsettled.
Because there is no systemic progesterone withdrawal before the onset of labor, a …

To explore how progesterone affects human pregnancy, we identified the progesterone
target cells within the fetal membranes (amnion, chorion, and decidua) at term by assessing …

Context: We examined whether human parturition involves functional progesterone
withdrawal mediated by changes in myometrial expression of progesterone receptors (PRs) …

In humans, progesterone levels are sustained before the onset of labour. Therefore, the
mechanism for parturition that has been proposed for humans is 'functional'progesterone …

Progesterone receptor (PR) is a member of the nuclear receptor superfamily. To date, two
isoforms of PR have been identified, PR-A and PR-B. In progesterone responsive tissues …

Background The mechanism that initiates human parturition has been proposed to
be'functional progesterone withdrawal'whereby the 116 kDa B-isoform of the progesterone …

The human placenta produces large quantities of progesterone, the function and target
tissues of action of which during pregnancy are not completely understood. Although it has …

In order for a successful pregnancy to occur, the embryo must attach to the luminal epithelial
cells and invade into the stroma. Then, the surrounding stromal cells need to undergo …

Progesterone acts to maintain uterine quiescence during pregnancy. In contrast to many
other species, no decrease in maternal serum levels of progesterone can be observed in …