Tocilizumab administration for the treatment of hospitalized patients with COVID‐19: a systematic review and meta‐analysis
C Kyriakopoulos, G Ntritsos, A Gogali, H Milionis… - …, 2021 - Wiley Online Library
Tocilizumab has been repurposed against the 'cytokine storm'in the setting of coronavirus
disease 2019 (COVID‐19). Our aim was to evaluate the efficacy of tocilizumab in the …
disease 2019 (COVID‐19). Our aim was to evaluate the efficacy of tocilizumab in the …
Tocilizumab in hospitalized patients with COVID-19: a meta analysis of randomized controlled trials
Background To date, only dexamethasone has been shown to reduce mortality in
coronavirus disease-19 (COVID-19) patients. Tocilizumab has been recently added to the …
coronavirus disease-19 (COVID-19) patients. Tocilizumab has been recently added to the …
Tocilizumab in COVID-19: a meta-analysis, trial sequential analysis, and meta-regression of randomized-controlled trials
Abstract Purpose Interleukin-6 (IL-6) levels discriminate between patients with mild and
severe COVID-19, making IL-6 inhibition an attractive therapeutic strategy. We conducted a …
severe COVID-19, making IL-6 inhibition an attractive therapeutic strategy. We conducted a …
Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID‐19; a systematic review and meta‐analysis of randomized clinical trials
Aims Tocilizumab has emerged as an important therapy in treating patients with coronavirus
disease (COVID‐19). Our purpose was to evaluate the efficacy and safety of tocilizumab …
disease (COVID‐19). Our purpose was to evaluate the efficacy and safety of tocilizumab …
Efficacy and safety of tocilizumab in severe and critical COVID-19: a systematic review and meta-analysis
S Rezaei, B Fatemi, Z Karimi Majd… - Expert review of …, 2021 - Taylor & Francis
Objectives Currently published papers and clinical guidelines regarding the effects of
tocilizumab in severe and critical COVID-19 are contradictory. The aim of this meta-analysis …
tocilizumab in severe and critical COVID-19 are contradictory. The aim of this meta-analysis …
Tocilizumab in patients hospitalized with COVID-19 pneumonia: systematic review and meta-analysis of randomized controlled trials
S Gupta, RP Padappayil, A Bansal… - Journal of …, 2022 - journals.sagepub.com
Tocilizumab is an interleukin receptor inhibitor that has been used in patients with COVID-19
pneumonia. There are recent randomized controlled trials (RCTs) that evaluated the efficacy …
pneumonia. There are recent randomized controlled trials (RCTs) that evaluated the efficacy …
The effect of tocilizumab on mortality in hospitalized patients with COVID-19: a meta-analysis of randomized controlled trials
Objective We aimed to perform a meta-analysis of randomized controlled trials (RCTs) to
summarize the overall effect of tocilizumab on the risk of mortality among patients with …
summarize the overall effect of tocilizumab on the risk of mortality among patients with …
[HTML][HTML] Efficacy and safety of tocilizumab in COVID-19 patients: a living systematic review and meta-analysis, first update
IM Tleyjeh, Z Kashour, M Riaz, L Hassett… - Clinical Microbiology …, 2021 - Elsevier
Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …
[HTML][HTML] Use of tocilizumab in COVID-19: a systematic review and meta-analysis of current evidence
S Kotak, M Khatri, M Malik, M Malik, W Hassan… - Cureus, 2020 - ncbi.nlm.nih.gov
Materials and methods Online databases (PubMed and Cochrane) were searched until
June 29, 2020, for original articles investigating the immunological response in COVID-19 …
June 29, 2020, for original articles investigating the immunological response in COVID-19 …
Beneficial and harmful outcomes of tocilizumab in severe COVID‐19: a systematic review and meta‐analysis
M Rubio‐Rivas, CG Forero… - … : The Journal of …, 2021 - Wiley Online Library
Introduction The results of studies of tocilizumab (TCZ) in COVID‐19 are contradictory. Our
study aims to update medical evidence from controlled observational studies and …
study aims to update medical evidence from controlled observational studies and …
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