Can selenium levels act as a marker of colorectal cancer risk?

MR Lener, S Gupta, RJ Scott, M Tootsi, M Kulp… - BMC cancer, 2013 - Springer
Background Selenium has attracted attention because of its antioxidant properties.
Antioxidants protects cells from damage. Certain breakdown products of selenium are …

Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort

DJ Hughes, V Fedirko, M Jenab… - … journal of cancer, 2015 - Wiley Online Library
Suboptimal intakes of the micronutrient selenium (Se) are found in many parts of Europe.
Low Se status may contribute to colorectal cancer (CRC) development. We assessed Se …

Selenium and colorectal adenomas risk: a meta-analysis

Y Ou, B Jiang, X Wang, W Ma, J Guo - Nutrition and cancer, 2012 - Taylor & Francis
Selenium, as an important component of some antioxidants, has been suggested to have
protective effects against colorectal adenomas. This meta-analysis examined the …

[HTML][HTML] Ecologic study of serum selenium and upper gastrointestinal cancers in Iran

M Nouraie, A Pourshams, F Kamangar… - World journal of …, 2004 - ncbi.nlm.nih.gov
AIM: Both observational and experimental studies have shown that higher selenium status
reduces the risk of upper gastrointestinal cancers in selenium deficient populations. Recent …

Serum selenium and colonic neoplastic risk

RL Nelson, FG Davis, E Sutter, JW Kikendall… - Diseases of the colon & …, 1995 - Springer
BACKGROUND: Selenium deficiency has been associated with cancer risk in several
organs. This association was investigated in neoplasia of the colorectum. DESIGN: A case …

Selenium and colorectal adenoma: results of a pooled analysis

ET Jacobs, R Jiang, DS Alberts… - Journal of the …, 2004 - academic.oup.com
Background: Secondary analyses of data from a large randomized clinical trial have
suggested that intake of the trace element selenium reduces risk of colorectal neoplasia, but …

Prediagnostic blood selenium status and mortality among patients with colorectal cancer in western european populations

JR Baker, S Umesh, M Jenab, L Schomburg… - Biomedicines, 2021 - mdpi.com
A higher selenium (Se) status has been shown to be associated with lower risk for colorectal
cancer (CRC), but the importance of Se in survival after CRC diagnosis is not well studied …

Selenium supplementation enhances low selenium levels and stimulates glutathione peroxidase activity in peripheral blood and distal colon mucosa in past and …

OH Al-Taie, J Seufert, S Karvar, C Adolph… - Nutrition and …, 2003 - Taylor & Francis
Selenoproteins such as glutathione peroxidases (GPx), thioredoxin reductases (TrxR), and
selenoprotein P (SePP) contain molecular selenium in form of selenocysteines within their …

Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women's Health Initiative Observational Study and meta …

Y Takata, AR Kristal, IB King, X Song… - … , biomarkers & prevention, 2011 - AACR
Background: Selenium may prevent colorectal cancer. However, several previous studies
are small and few investigated the association between selenium and colorectal cancer …

High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal cancer early detection program

U Peters, N Chatterjee, TR Church, C Mayo… - … Biomarkers & Prevention, 2006 - AACR
Background: Epidemiologic and animal studies suggest that selenium may reduce risk of
colorectal cancer. However, the epidemiologic data is mainly from relatively small …