[HTML][HTML] Systems biology in inflammatory bowel diseases: on the way to precision medicine
Inflammatory bowel diseases (IBD) are chronic and recurrent inflammatory disorders of the
gastrointestinal tract. The elucidation of their etiopathology requires complex and multiple …
gastrointestinal tract. The elucidation of their etiopathology requires complex and multiple …
Inflammatory bowel disease meets systems biology: a multi-omics challenge and frontier
O Palmieri, T Mazza, S Castellana, A Panza… - OMICS: A Journal of …, 2016 - liebertpub.com
The inflammatory bowel disease (IBD) is a systemic disease that is characterized by the
inflammation of the gastrointestinal tract. It includes ulcerative colitis and the Crohn's …
inflammation of the gastrointestinal tract. It includes ulcerative colitis and the Crohn's …
IBD systems biology is here to stay
C Fiocchi, D Iliopoulos - Inflammatory bowel diseases, 2021 - academic.oup.com
Background Systems biology is a rapidly advancing field of science that allows us to look
into disease mechanisms, patient diagnosis and stratification, and drug development in a …
into disease mechanisms, patient diagnosis and stratification, and drug development in a …
[HTML][HTML] Network biology approaches to achieve precision medicine in inflammatory bowel disease
JP Thomas, D Modos, T Korcsmaros… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a chronic immune-mediated condition arising due to
complex interactions between multiple genetic and environmental factors. Despite recent …
complex interactions between multiple genetic and environmental factors. Despite recent …
Network analysis of inflammatory bowel disease research: towards the interactome
ME Fernandez, FN Nazar, LB Moine… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Modern views accept that inflammatory bowel diseases [IBD]
emerge from complex interactions among the multiple components of a biological network …
emerge from complex interactions among the multiple components of a biological network …
[HTML][HTML] An integrative analysis of gene expression and molecular interaction data to identify dys-regulated sub-networks in inflammatory bowel disease
Background Inflammatory bowel disease (IBD) consists of two main disease-subtypes,
Crohn's disease (CD) and ulcerative colitis (UC); these subtypes share overlapping genetic …
Crohn's disease (CD) and ulcerative colitis (UC); these subtypes share overlapping genetic …
Systems biology in inflammatory bowel diseases: ready for prime time
C Polytarchou, G Koukos… - Current opinion in …, 2014 - journals.lww.com
A systems biology approach could potentially identify the central regulators (hubs) in the IBD
interactome and improve our understanding of the molecular mechanisms involved in IBD …
interactome and improve our understanding of the molecular mechanisms involved in IBD …
Systems biology approaches for inflammatory bowel disease: emphasis on gut microbial metabolism
Although the prevalence of main idiopathic forms of inflammatory bowel disease (IBD) has
risen considerably over the last decades, their clinical features do not allow accurate …
risen considerably over the last decades, their clinical features do not allow accurate …
[HTML][HTML] Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets
PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …
disruption has been associated with several diseases, including Crohn's disease and …
[HTML][HTML] Systems biology approach highlights mechanistic differences between Crohn's disease and ulcerative colitis
PA Ruiz Castro, H Yepiskoposyan, S Gubian… - Scientific Reports, 2021 - nature.com
The molecular mechanisms of IBD have been the subject of intensive exploration. We,
therefore, assembled the available information into a suite of causal biological network …
therefore, assembled the available information into a suite of causal biological network …
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