Cells in the body reside within the extracellular matrix (ECM), a three-dimensional
environment that not only provides structural support for the cells, but also influences cellular …

Stem cell fate is closely intertwined with microenvironmental and endogenous cues within
the body. Recapitulating this dynamic environment ex vivo can be achieved through …

Traditional synthetic substrates and matrices for cell culture have proven to be of only limited
utility in efforts to understand and control cell behavior, in large part because they fail to …

Important advances in the field of tissue engineering are arising from increased interest in
novel biomaterial designs with bioactive components that directly influence cell behavior …

In the biological microenvironment, cells are surrounded by an extracellular matrix (ECM),
with which they dynamically interact during various biological processes. Specifically, the …

The human body is complex and hierarchically structured, composed of cells residing within
the extracellular matrix (ECM) of tissues that are assembled into organs, all working together …

Smart or stimuli-responsive materials are an emerging class of materials used for tissue
engineering and drug delivery. A variety of stimuli (including temperature, pH, redox-state …

The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …

The extracellular matrix (ECM) is a highly dynamic system that constantly offers physical,
biological, and chemical signals to embraced cells. Increasing evidence suggests that …

Across diverse research and application areas, dynamic functionality—such as
programmable changes in biochemical property, in mechanical property, or in microscopic …