Neoadjuvant chemotherapy (NAC) is increasingly being used in the treatment of locally
advanced breast cancer as well as for early breast cancer. Axillary lymph node dissection …

Importance The increasing use of neoadjuvant chemotherapy (NAC) for operable breast
cancer has raised questions about optimal local therapy for the axilla. Observations Sentinel …

Background Neoadjuvant chemotherapy (NAC) downstages axillary disease in 55% of node-
positive (N1) breast cancer. The feasibility and accuracy of sentinel lymph node biopsy …

Several contemporary trials have demonstrated that neoadjuvant chemotherapy can
increase the likelihood of both resectability for patients who have inoperable breast cancer …

Neoadjuvant chemotherapy is the standard of care for patients with locally advanced breast
cancer and is a reasonable alternative to adjuvant chemotherapy for those with large …

Surgical management of the axilla in breast cancer has been a topic of great interest. While
sentinel lymph node biopsy (SLNB) is an established approach for patients undergoing …

Background Targeted axillary dissection, which combines sentinel lymph node biopsy with
removal of the proven involved node noted during the staging process, has been shown to …

Use of sentinel lymph node biopsy for axillary staging of patients with breast cancer treated
with neoadjuvant chemotherapy has been widely debated. Questions arise regarding the …

Simple Summary Axillary status is crucial for determining the correct local and systemic
treatment. The possibility of de-escalating axillary surgery in patients with breast cancer …

Sentinel node biopsy is rapidly evolving as an alternative to Level I and II axillary node
dissection for staging of patients with operable breast cancer. A large number of single …