The adenosine A3 receptor was initially cloned from a rat testis cDNA library. 4
Subsequently, A3 receptors have been cloned from human, 5, 6 sheep, 7 mouse, 8 and …

The activation of the human A3 adenosine receptor (AR) by a wide range of N6-substituted
adenosine derivatives was studied in intact CHO cells stably expressing this receptor …

The purified bovine brain A1-adenosine receptor has previously been shown to discriminate
among closely related G protein alpha-subunits. To obtain analogous information for the …

The potency of adenosine and inosine as agonists at human adenosine receptors was
examined in a functional assay using changes in cyclic AMP (cAMP) formation in intact …

We have used the polymerase chain reaction technique to selectively amplify guanine
nucleotide-binding regulatory protein (G protein)-coupled receptor cDNA sequences from rat …

Adenosine acts as a cytoprotective modulator in response to stress to an organ or tissue.
Although short-lived in the circulation, it can activate four subtypes of G protein-coupled …

Ligand recognition has been extensively explored in G protein-coupled A 1, A 2A, and A 2B
adenosine receptors but not in the A 3 receptor, which is cerebroprotective and …

Responses to adenosine are governed by selective activation of distinct G proteins by
adenosine receptor (AR) subtypes. The A 2a AR couples via G s to adenylyl cyclase …

A cDNA encoding a G protein-coupled receptor of unknown ligand specificity was isolated
from a human hippocampal cDNA library by virtue of the high degree of structural homology …

The adenosine A2a receptor belongs to the seven transmembrane helix G‐protein‐coupled
receptor family, is abundant in striatum, vasculature and platelets and is involved in several …