The distribution, molecular structure and role of adenosine A2 receptors in the nervous
system, is reviewed. The adenosine A2a receptor subtype, identified in the nervous system …

Adenosine acts as a neurotransmitter in the brain through the activation of four specific G‐
protein‐coupled receptors (the A1, A2A, A2B, and A3 receptors). The A1 receptor has long …

Adenosine is involved in a range of physiological and pathological effects through
membrane-bound receptors linked to G proteins. There are four subtypes of adenosine …

Adenosine exerts its effects through four subtypes of G‐protein‐coupled receptors (GPCRs):
adenosine A1 and A3 receptors (A3R), which generally couple to Gi proteins and adenosine …

Using the sequence conservation in the G protein-coupled receptor superfamily, we have
isolated an adenosine A 1 receptor cDNA from a human hippocampal cDNA library by …

With the recent purification and cloning of the A1AR and the cloning of the A2AR in
association with the development of selective radioligands, we are now poised to begin to …

The adenosine A 2B receptor (A 2B AR) is one of four adenosine receptor subtypes
belonging to the Class A family of G protein-coupled receptors (GPCRs). Until recently, the A …

The class A adenosine A1 receptor (A1R) is a G-protein-coupled receptor that preferentially
couples to inhibitory Gi/o heterotrimeric G proteins, has been implicated in numerous …

A 3 adenosine receptor (A 3 AR) activation contributes to both the cardioprotective and
antihypertensive effects of adenosine. To date, no studies have examined the mechanisms …

The A2A adenosine receptor (A2A‐AR) transcript and radioligand binding sites have a
distinct distribution in rat brain, restricted primarily to the striatum, nucleus accumbens and …