Abstract Selective IgE deficiency (IgED) is currently defined as a significant decrease in
serum levels of IgE (< 2 kIU/L) in a patient whose other immunoglobulin levels are normal …

Purpose Combined immunodeficiency (CID) presents a unique challenge to clinicians. Two
patients presented with the prior clinical diagnosis of common variable immunodeficiency …

Background Recently, a growing number of novel genetic defects underlying primary
immunodeficiencies (PIDs) have been identified, increasing the number of PID up to more …

Common Variable Immunodeficiency Disorders (CVID) are the most frequent symptomatic
primary immune deficiency (PID) in adults. Current estimates suggest a prevalence of∼ 1 …

Introduction: Severe combined immunodeficiency (SCID) is known as a pediatric emergency
disease with life threatening conditions. This is an exclusive report of clinical evaluation …

Introduction Sixty-four primary immunodeficiency patients were registered at the Pediatric
Allergy and Immunology Department, Children's Hospital, Ain Shams University, Cairo …

Objective To summarize the current understanding of diagnostic and postdiagnostic
evaluation of common variable immunodeficiency (CVID). Data Sources PubMed Central …

Primary immunodeficiencies (PIDs) are a heterogeneous group of monogenic inborn errors
of immunity. The genetic causes of these diseases can be identified using whole exome …

Purpose We aimed to achieve a retrospective molecular diagnosis by applying state-of-the-
art genomic sequencing methods to past patients with T-B+ NK+ severe combined …

Inborn errors of immunity (IEI), formerly known as primary immunodeficiency disorders
(PIDs), are inherited disorders caused by damaging germline variants in single genes …