Ingestion of energy rich high fat diets is one of the determining factors associated with the
obesity epidemic. Therefore, much can be learned from studies of obesity-related …

Aim Gamma‐aminobutyric acid (GABA)‐ergic transmission from the hypothalamus is
essential for normal feeding regulation, and hyperphagia can be induced by local …

Background Obesity is currently one of the major causes of ill health and it is clear that
overeatingis the cause of obesity. However, the actions of many endogenous factors that …

Obesity is an increasing problem and identification of the driving forces for overeating of
energy‐rich food is important. Previous studies show that the stress and sex steroid …

Obesity is strongly associated with ill health, primarily caused by consumption of excessive
calories, and promoted (inter alia) by gamma-amino-butyric-acid (GABA) stimulating food …

Background/Aims: Allopregnanolone or 3α-hydroxy-5α-pregnan-20-one (AlloP) is normally
sedative and anxiolytic, but can under provoking circumstances paradoxically induce …

The progesterone metabolite, allopregnanolone (AlloP), is a GABA A receptor modulating
steroid and is known to have orexigenic and pro-obesity effects. The neurobiological …

The present studies were undertaken to investigate the neuroactive steroidal modulation of
feeding behavior and possible involvement of γ-aminobutyric acid type-A (GABA-A) and …

Like benzodiazepines receptor (BDZR) ligands, 3α-hydroxylated, 5α, or 5β pregnane
steroids are sedative, anticonvulsant, and anxiolytic. BDZR ligands also modulate the …

The pharmacological profile of allopregnanolone, a neuroactive steroid that is a potent
positive modulator of γ-aminobutyric acidA (GABAA) receptors, is similar to that of ethanol …