Adipose tissue is a critical regulator of systemic metabolism and normal bodily homeostasis.
Recently, the immune system has been implicated in the regulation of adipose tissue …

Glucose is a vital source of energy for all mammals. The balance between glucose uptake,
metabolism and storage determines the energy status of an individual, and perturbations in …

Obesity is an increasingly prevalent disease worldwide. While genetic and environmental
factors are known to regulate the development of obesity and associated metabolic …

Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

Over the past decade, chronic inflammation in visceral adipose tissue (VAT) has gained
acceptance as a lead promoter of insulin resistance in obesity. A great deal of evidence has …

Adipose tissue (AT) plays a pivotal role in whole-body lipid and glucose homeostasis. AT
exerts metabolic control through various immunological mechanisms that instigated a new …

Adipose tissue is composed of many functionally and developmentally distinct cell types, the
metabolic core of which is the adipocyte. The classification of “adipocyte” encompasses …

Obesity is a major risk factor for metabolic disease, with white adipose tissue (WAT)
inflammation emerging as a key underlying pathology. Alongside its major role in energy …

Inflammation is an important contributor to the pathogenesis of obesity-related type 2
diabetes (T2D). Adipose tissue-resident immune cells have been observed, and the …

Metabolic disorders, such as obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver
disease, are characterized by chronic low-grade tissue and systemic inflammation. During …