Physical–cognitive activity has long-lasting beneficial effects on the brain and on behavior.
Environmental enrichment (EE) induces brain activity known to influence the behavior of …

Stress exposure is associated with individual differences in corticolimbic structure and
function that often mirror patterns observed in psychopathology. Gene x environment …

Mental health is central to normal health outcomes. A widely accepted theory is that chronic
persistent stress during adulthood as well as during early life triggers onset of …

The fact that exposure to severe stress leads to the development of psychiatric disorders
serves as the basic rationale for animal models of stress disorders. Clinical and …

Stress initiates adaptive processes that allow the organism to physiologically cope with
prolonged or intermittent exposure to real or perceived threats. A major component of this …

Stress encompasses profound psychological and physiological changes that are observable
on all levels, from cellular mechanisms, humoral changes, and brain activation to subjective …

The medial prefrontal cortex (mPFC) receives information regarding stimuli and
appropriately orchestrates neurophysiological, autonomic, and behavioral responses to …

Strong psychologically stressful events are known to have a long-lasting impact on behavior.
The consolidation of such, largely adaptive, behavioral responses to stressful events …

Clinical evidence indicates that serotonin-1A receptor (5-HT 1A R) gene polymorphisms are
associated with anxiety disorders and deficits in cognition. In animal models, exercise (Ex) …

Early life stress (ELS), such as abuse, neglect, and maltreatment, exhibits a strong impact on
the brain and mental development of children. However, it is not fully understood how ELS …