The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating
interactions between blood cells and the endothelium, and also because of the possible use …

P-selectin (CD62P, previously also known as GMP-140 and PADGEM) is, alongside E-
selectin (CD62E) and L-selectin (CD62L), a member of the selectin family of adhesion …

Activated platelets are key components in many arterial disorders. P-selectin is an activation-
dependent platelet receptor, which is also identified in endothelial cells. Together with E-and …

P-selectin is a member of the selectin family of cell adhesion molecules which are important
in the transient attachment of leukocytes to endothelial cells and platelets. A number of …

Background: P-selectin, an integral membrane glycoprotein of platelets and endothelial
cells, is rapidly redistributed to the cell surface after cellular activation. The soluble form of P …

Background—P-selectin, a cell-surface adhesion molecule involved in leukocyte rolling and
attachment, has been hypothesized to play a role in the initiation of atherosclerosis …

Abstract P-selectin (GMP-140) is an adhesion molecule present within endothelial cells that
is rapidly translocated to the cell membrane upon activation, where it mediates endothelial …

von Willebrand factor and soluble thrombomodulin are established plasma markers of
endothelial cell dysfunction, whilst beta thromboglobulin is an established plasma marker of …

The initial steps in the pathogenesis of atherosclerosis involve changes to the vascular
endothelium, which produces numerous substances involved in the regulation and …

Background—Hypercholesterolemia is considered a major risk factor for the development of
atherosclerosis. Enhanced lipid peroxidation and persistent platelet activation can be …