Essential protein detection by random walk on weighted protein-protein interaction networks
B Xu, J Guan, Y Wang, Z Wang - IEEE/ACM Transactions on …, 2017 - ieeexplore.ieee.org
Essential proteins are critical to the development and survival of cells. Identification of
essential proteins is helpful for understanding the minimal set of required genes in a living …
essential proteins is helpful for understanding the minimal set of required genes in a living …
Random walk based method to identify essential proteins by integrating network topology and biological characteristics
Essential proteins are regarded as the fundamental components of living organisms. The
identification of essential proteins greatly contributes to the understanding of cellular …
identification of essential proteins greatly contributes to the understanding of cellular …
A seed expansion-based method to identify essential proteins by integrating protein–protein interaction sub-networks and multiple biological characteristics
H Zhao, G Liu, X Cao - BMC bioinformatics, 2023 - Springer
Background The identification of essential proteins is of great significance in biology and
pathology. However, protein–protein interaction (PPI) data obtained through high …
pathology. However, protein–protein interaction (PPI) data obtained through high …
Detecting essential proteins based on network topology, gene expression data, and gene ontology information
W Zhang, J Xu, Y Li, X Zou - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
The identification of essential proteins in protein-protein interaction (PPI) networks is of great
significance for understanding cellular processes. With the increasing availability of large …
significance for understanding cellular processes. With the increasing availability of large …
A random walk-based method for detecting essential proteins by integrating the topological and biological features of PPI network
NM Ahmed, L Chen, B Li, W Liu, C Dai - Soft Computing, 2021 - Springer
The essential protein detection on protein–protein interaction (PPI) network can not only
promote the research of life science, but also have important applications in disease …
promote the research of life science, but also have important applications in disease …
A new method for the discovery of essential proteins
Background Experimental methods for the identification of essential proteins are always
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
costly, time-consuming, and laborious. It is a challenging task to find protein essentiality only …
Identifying essential proteins from active PPI networks constructed with dynamic gene expression
Essential proteins are vitally important for cellular survival and development, and identifying
essential proteins is very meaningful research work in the post-genome era. Rapid increase …
essential proteins is very meaningful research work in the post-genome era. Rapid increase …
Essential protein recognition via community significance
Y Liu, W Chen, Z He - IEEE/ACM Transactions on …, 2021 - ieeexplore.ieee.org
Essential protein plays a vital role in understanding the cellular life. With the advance in high-
throughput technologies, a number of protein-protein interaction (PPI) networks have been …
throughput technologies, a number of protein-protein interaction (PPI) networks have been …
Identification of essential proteins based on edge clustering coefficient
Identification of essential proteins is key to understanding the minimal requirements for
cellular life and important for drug design. The rapid increase of available protein-protein …
cellular life and important for drug design. The rapid increase of available protein-protein …
Identification of essential proteins based on ranking edge-weights in protein-protein interaction networks
Essential proteins are those that are indispensable to cellular survival and development.
Existing methods for essential protein identification generally rely on knock-out experiments …
Existing methods for essential protein identification generally rely on knock-out experiments …